Research advances on the mechanism of extracellular vesicles of adipose-derived mesenchymal stem cells in promoting wound angiogenesis

Ju Yikun; Fang Bairong

doi:10.3760/cma.j.cn501225-20220322-00080

Volume 39 Issue 1

Jan. 2023

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Article Navigation > CHINESE JOURNAL OF BURNS AND WOUNDS > 2023 > 39(1): 85-90

Li Shaohui, Zhang Wanfu, Hu Xiaolong, et al. Clinical application of negative-pressure wound therapy in split-thickness skin grafting at hard-to-fix sites[J]. Chin j Burns, 2020, 36(7): 528-533. Doi: 10.3760/cma.j.cn501120-20200224-00086

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Ju YK,Fang BR.Research advances on the mechanism of extracellular vesicles of adipose-derived mesenchymal stem cells in promoting wound angiogenesis[J].Chin J Burns Wounds,2023,39(1):85-90.DOI: 10.3760/cma.j.cn501225-20220322-00080.

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Research advances on the mechanism of extracellular vesicles of adipose-derived mesenchymal stem cells in promoting wound angiogenesis

doi: 10.3760/cma.j.cn501225-20220322-00080

Ju Yikun,
Fang Bairong^,

Department of Plastic and Aesthetic (Burn) Surgery, the Second Xiangya Hospital, Central South University, Changsha 410011, China

Funds:

Natural Science Foundation of Hunan Provincial of China 2021JJ30928

More Information

Corresponding author: Fang Bairong, Email: fbrfbr2004@csu.edu.cn
Received Date: 2022-03-22

Abstract

Abstract

Wound healing involves complex pathophysiological mechanism, among which angiogenesis is considered as one of the key steps in wound healing, and promoting wound angiogenesis can accelerate wound healing. In recent years, mesenchymal stem cell-derived extracellular vesicles have been proven to produce equivalent effects of wound healing promotion comparable to stem cell therapy, with the advantages of low antigenicity and high biocompatibility. The specific mechanism by which extracellular vesicles facilitate wound healing is still not fully understood and is thought to involve all stages of wound healing. This article focuses on the possible mechanism of extracellular vesicles of adipose-derived mesenchymal stem cells in promoting wound angiogenesis, so as to provide ideas for further study on the mechanism of extracellular vesicles to promote wound healing.
- Mesenchymal stem cells,
- Neovascularization, physiologic,
- Wound healing,
- Extracellular vesicles

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References(63)

References

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Research advances on the mechanism of extracellular vesicles of adipose-derived mesenchymal stem cells in promoting wound angiogenesis

doi: 10.3760/cma.j.cn501225-20220322-00080

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Research advances on the mechanism of extracellular vesicles of adipose-derived mesenchymal stem cells in promoting wound angiogenesis

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