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2025 Vol. 41, No. 2

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2025, 41(2): 101-101. doi: 10.3760/cma.j.cn501225-20250119-00029
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2025, 41(2): 102-102. doi: 10.3760/cma.j.cn501225-20250123-00034
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2025, 41(2): 103-105. doi: 10.3760/cma.j.cn501225-20250107-00012
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2025, 41(2): 106-108. doi: 10.3760/cma.j.cn501225-20250123-00033
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Expert Forum
New progresses in thumb and finger reconstruction
Wang Zengtao, Liu Huanlong, Hao Liwen, Qiu Shenqiang, Liu Linfeng, Chen Chao
2025, 41(2): 109-119. doi: 10.3760/cma.j.cn501225-20240814-00305
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For centuries, people have been searching for ways to reconstruct the mutilated thumb and fingers. Among the hundreds of operation methods that have appeared, the method of toe transplantation to reconstruct the thumb and fingers, which appeared in the second half of the 19th century, had the best e...
Mechanisms and intervention strategies of angiogenesis disorders in diabetic foot ulcers
Tao Ke, Cao Tao, Hao Tong
2025, 41(2): 120-126. doi: 10.3760/cma.j.cn501225-20241204-00474
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Nerve and vascular damage are important factors affecting the occurrence and development of diabetic foot ulcer (DFU). Lower extremity vascular injury combined with microangiogenesis disorder caused by various factors including hyperglycemia, neurotrophic impairment, ischemia, hypoxia, and infection...
Original Article·Diabetic Wounds
Effect and mechanism of Andrias davidianus skin mucopolysaccharides on full-thickness skin defect wound healing in diabetic mice
Gou Weiming, Yang Peng, Lu Yifei, Zhang Xiaorong, Qin Yiming, Li Jingyuan, Huang Yong, Zhang Qing, Luo Gaoxing
2025, 41(2): 127-136. doi: 10.3760/cma.j.cn501225-20240725-00280
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Objective To explore the effect and mechanism of Andrias davidianus skin mucopolysaccharides (ASMP) on full-thickness skin defect wound healing in diabetic mice. Methods This study was an experimental study. The ASMP with polysaccharide content of (70.0±0.3)% was prepared; the proliferation activity...
Targeted energy metabolomics study on wound tissue of diabetic rats
Wang Xiaoyang, Hu Yujie, Wang Xiaochuan, Zhao Jie, Zhang Jixun, Jiang Duyin
2025, 41(2): 137-144. doi: 10.3760/cma.j.cn501225-20241014-00385
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Objective To explore the change of energy metabolism in wound tissue of diabetic rats. Methods This study was an experimental study. Six 8-week-old male Sprague-Dawley rats were divided into diabetic group inflicted with a diabetic full-thickness skin defect wound and control group only inflicted wi...
Influence and mechanism of bone marrow mesenchymal stem cells overexpressing growth arrest specific 6 on full-thickness skin defect wounds in diabetic mice
Liu Pei, Wang Chao, Wei Qijian, Li Yuteng, Cui Lijun, Wang Changchuan, Zhang Fan, Ma Ling, Tian Xuan
2025, 41(2): 145-154. doi: 10.3760/cma.j.cn501225-20241024-00409
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Objective To investigate the influence and mechanism of bone marrow mesenchymal stem cells (BMSCs) overexpressing growth arrest specific 6, i.e. GAS6/BMSCs on full-thickness skin defect wounds in diabetic mice. Methods This study was an experimental study. Twelve 8-week-old male C57BL/6J mice were d...
Original Article
Effect of self-made static progressive braces in the stepwise treatment of hand flexion dysfunction caused by scar contracture after burn injury
Zhao Haiyang, Zhou Qin, Liu Jiaqi, Zhang Wanfu, Zhu Chan, Xu Jing, Han Juntao, Hu Dahai, Guan Hao
2025, 41(2): 155-162. doi: 10.3760/cma.j.cn501225-20240606-00216
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Objective To explore the effect of self-made static progressive braces in the stepwise treatment of hand flexion dysfunction caused by scar contracture after burn injury. Methods This study was a retrospective observational study. From January 2022 to March 2024, the First Affiliated Hospital of Air...
Research on the feasibility of dynamic contrast-enhanced magnetic resonance imaging in assessing the microcirculatory perfusion of skeletal muscle in rabbit limbs in the early stage after high-voltage electric burns
Ruan Peng, Sun Siqin, Ge Yinghong, Zha Yunfei
2025, 41(2): 163-170. doi: 10.3760/cma.j.cn501225-20240517-00183
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Objective To explore the feasibility of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in assessing the microcirculatory perfusion of skeletal muscle in rabbit limbs in the early stage after high-voltage electric burns. Methods This study was an experimental study. Thirty-two male bi...
Establishment and clinical application effects of a three-dimensional navigation process for design and resection of perforator flaps based on multi-detector computed tomography angiography
Yin Qixiang, Mi Jingyi, Cai Huazhong, Zhou Feng, Yao Qun, Hua Yong
2025, 41(2): 171-179. doi: 10.3760/cma.j.cn501225-20240407-00123
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Objective To establish a three-dimensional navigation process for design and resection of perforator flaps based on multi-detector computed tomography angiography (MDCTA) and to explore its clinical application effects. Methods This study was a retrospective observational study. From January 2021 to...
Mendelian randomization analysis of the causal relationships between human inflammatory proteins and keloids
Li Tao, Zhu Chenchen, Chen Jinyuan, Li Puzhen, Jin Peisheng, Li Xueyang
2025, 41(2): 180-187. doi: 10.3760/cma.j.cn501225-20240526-00198
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Objective To explore the causal relationships between human inflammatory proteins and keloids. Methods This study was based on Mendelian randomization (MR) analysis. Human inflammatory proteins were considered as the exposure factors, and keloid was considered as the outcome. Data on 91 inflammatory...
Review
Research advances on the application of recombinant human collagen biomaterials in the field of tissue engineering
Liu Huan, Aobuliaximu Yakupu, Jin Ronghua, Zhang Wei, Han Chunmao, Wang Xingang
2025, 41(2): 188-194. doi: 10.3760/cma.j.cn501225-20240229-00081
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Extensive tissue and organ defects caused by major trauma and burns are common problems in clinical practice. Recombinant human collagen biomaterials, with advantages including impeccable biocompatibility, customization, stable amino acid sequence, low immunogenicity, and inherent biodegradation, ha...
Research advances on the effects of mechanical forces on epithelial cells
Pang Jiayuecheng, Duanmu Ying, Jin Shunxin, Fang Xiaowan, Xiao Shichu, Xia Zhaofan
2025, 41(2): 195-200. doi: 10.3760/cma.j.cn501225-20240611-00222
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There are multiple signaling communication modalities for the biological activities of single cells or groups of cells. The elucidated modalities include neuronal electrical signal communication, long-distance communication mediated by hormones, and short-range signal communication secreted by cells...

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