再生生物技术治疗糖尿病足溃疡的研究进展

游兴; 孙广峰; 魏在荣

doi:10.3760/cma.j.cn501225-20241119-00454

再生生物技术治疗糖尿病足溃疡的研究进展

doi: 10.3760/cma.j.cn501225-20241119-00454

1.
遵义医科大学第二附属医院烧伤整形外科,遵义　563000
2.
遵义医科大学附属医院烧伤整形外科,遵义　563003

基金项目:

国家自然科学基金地区科学基金项目 82360445

省部共建协同创新中心 2020-39

贵州省卫生健康委员会科学技术基金项目 gzwkj2021-226

详细信息

通讯作者:
魏在荣,Email：zairongwei@163.com

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- 文章访问数: 75
- HTML全文浏览量: 46
- PDF下载量: 11
- 被引次数: 0
出版历程
- 收稿日期: 2024-11-19
- 网络出版日期: 2025-12-22

Research advances on the treatment of diabetic foot ulcers with regenerative biotechnologies

1.
Department of Burns and Plastic Surgery, the Second Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China
2.
Department of Burns and Plastic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi 563003, China

Funds:

Regional Science Foundation Project of National Natural Science Foundation of China 82360445

Collaborative Innovation Center of Chinese Ministry of Education 2020-39

Science and Technology Foundation of Health Commission of Guizhou Province gzwkj2021-226

More Information

Corresponding author: Wei Zairong, Email: zairongwei@163.com

摘要

摘要: 糖尿病足溃疡（DFU）作为糖尿病的严重并发症,因其愈合缓慢和高复发率而成为临床的一大挑战。近年来,随着再生医学的快速发展,DFU的治疗策略迎来了革新。该文系统综述了再生生物技术在DFU治疗中的应用现状,重点聚焦于干细胞疗法、生物材料工程及生长因子疗法等关键领域的最新研究进展,以期为未来的研究方向和临床应用提供科学依据。
- 糖尿病足 /
- 足溃疡 /
- 干细胞 /
- 生物相容性材料 /
- 慢性创面 /
- 创面修复 /
- 生长因子
Abstract: Diabetic foot ulcer (DFU), a severe complication of diabetes, poses a significant clinical challenge due to its slow healing and high recurrence rate. In recent years, with the rapid advancement of regenerative medicine, the treatment strategies for DFU have undergone a revolution. This review systematically reviews the application status of regenerative biotechnologies in DFU treatment, with a specific focus on recent progresses in key areas including stem cell therapy, biomaterials engineering, and growth factor-based therapeutics. It aims to provide a scientific foundation for future research directions and clinical translation.
- Diabetic foot /
- Foot ulcer /
- Stem cells /
- Biocompatible materials /
- Chronic wounds /
- Wound repair /
- Growth factors
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参考文献(47)

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