基于纳米生物材料技术的脓毒症治疗新策略

姚咏明; 张卉; 董宁

doi:10.3760/cma.j.cn501225-20241122-00458

基于纳米生物材料技术的脓毒症治疗新策略

doi: 10.3760/cma.j.cn501225-20241122-00458

解放军总医院医学创新研究部、第四医学中心,北京　　100853

基金项目:

国家重点研发计划 2022YFA1104604

国家自然科学基金重点项目 82241062

国家自然科学基金面上项目 82472194

详细信息

通讯作者:
姚咏明,Email：c_ff@sina.com

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- 被引次数: 0
出版历程
- 收稿日期: 2024-11-22

New strategy for sepsis treatment based on nanobiomaterial technology

Medical Innovation Research Department and the Fourth Medical Center of PLA General Hospital, Beijing 100853, China

Funds:

National Key Research and Development Program of China 2022YFA1104604

Key Program of National Natural Science Foundation of China 82241062

General Program of National Natural Science Foundation of China 82472194

More Information

Corresponding author: Yao Yongming, Email: c_ff@sina.com

摘要

摘要: 脓毒症的病理生理机制复杂,主要涉及过度炎症反应和免疫功能紊乱。纳米生物材料技术的发展给脓毒症治疗带来了全新选择。该文从抗菌、抗炎、靶向调控免疫细胞功能、多靶向联合调控等方面论述了纳米生物材料在脓毒症治疗中的应用现状和潜力,为未来开发基于纳米生物材料的脓毒症治疗策略开辟新方向。
- 脓毒症 /
- 生物相容性材料 /
- 纳米颗粒 /
- 药物递送系统
Abstract: The pathophysiological mechanisms underlying sepsis is complex, mainly involving excessive inflammatory response and immune dysfunction. The development of nanobiomaterial technology has brought brand-new options for the treatment of sepsis. In the current paper, we discuss the current application status and potential of nanobiomaterials in treatment of sepsis from aspects of antibacterial, anti-inflammatory, targeted regulation of immune cell function, and multi-target combined regulation, pointing out new direction for the future development of therapeutic strategies for sepsis based on nanobiomaterials.
- Sepsis /
- Biocompatible materials /
- Nanoparticle /
- Drug delivery system
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