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2003 Vol. 19, No. Z1

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Original Article
Experimental studies on the biocompatibility of spongy PLGA-collagen membrane as a tissue-engineering dermal scaffold
TIAN Jian-guang, BAI Dong-hai, LIU Zhi-guo, TANG Hong-tai, XIA Zhao-fan
2003, 19(Z1): 1-4. doi: 10.3760/cma.j.issn.1009-2587.2003.Z1.101
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Objective To evaluate the biocompatibility of spongy PLGA-collagen membrane as a dermal scaffold. Methods Adult SD rats, cultured human keratinocytes and fibroblasts were employed in the study. The in vivo degradation process and the in vitro cytotoxicity and hemolytic response of the PLGA-collagen ...
Effects of thrombin peptides and thrombin on the release of TGF-β and VEGF from human fibroblasts
HUANG Yue-sheng, YANG Zhong-cheng
2003, 19(Z1): 5-7. doi: 10.3760/cma.j.issn.1009-2587.2003.Z1.102
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Objective To explore the effect of thrombin peptide 508 (TP508) and thrombin on the release of TGF-β and VEGF from cultured human fibroblasts( Lu13 ) in vitro. Methods TP508 and thrombin in different concentrations were added to the confluent cultured Lu13 and incubated for 8 to 24 hours. Then the s...
A preliminary report of therapeutic effects of topical capsaicin in postburn hypertrophic scar
XU Ming-huo, CHAI Jia-ke, LU Jun-ling, CHEN Bao-ju, SHENG Zhi-yong, WANG Shi-ling
2003, 19(Z1): 8-10. doi: 10.3760/cma.j.issn.1009-2587.2003.Z1.103
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Objective To observe the therapeutic effects of capsaicin on hypertrophic scar ( HS). Methods 12 patients with hypertrophic scar within 3 months were randomly selected for a double-blind study. Each patient received two treatments, 0.05% capsaicin cream for one area of HS, cream vehicle for adjacent...
A study on the promoting effect of L-arginine on the burn wound healing of the rats with diabetes
GE Kui, LU Shu-liang, QING Chun, XIE Ting, NIU Yi-wen, RONG Liu, WANG Min-jun, LIN Wei-dong, JIN Shu-wen, HUA Lan-nv
2003, 19(Z1): 11-14. doi: 10.3760/cma.j.issn.1009-2587.2003.Z1.105
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Objective To explore the effect and possible mechanism of L-arginine on burn wound healing of the rats with diabetie. Methods One hundred and twenty three Spraque-Dawley( SD) rats were enrolled in the study and randomly divided into four groups. i. e. group A (thirty rats as normal control),group B(...
Expression of microtubule destabilizer-oncoprotein18/stathmin gene in the hypertrophic scar before and after the healing of the deep partial thickness burn wounds
YAO Qing-jun, JIA Chi-yu, CHEN Bi, LU Ning, XU Ming-da, LIU Xin-ping, YAO LI-bo, WANG Shu-sen
2003, 19(Z1): 15-17. doi: 10.3760/cma.j.issn.1009-2587.2003.Z1.107
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Objective To study the expression of microtubule destabilizer-oncoprotein18/stathmin (Op18) gene in the hypertrophic scar before and after the healing of the deep partial thickness burn wound. Methods Total RNA was extracted from the hypertrophic scar of the patients with deep partial thickness burn...
Effects of Ulinastatin on the intestinal mucosal barrier of the mini - pigs after severe burn injury
HU Xiaohua, GE Yan-ling, XIN Dong, LI Hai-bo, ZHANG Hui-ying, SUN Yong-hua
2003, 19(Z1): 18-21. doi: 10.3760/cma.j.issn.1009-2587.2003.Z1.108
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Objective To explore the protective effect of a human proteinkinase inhibitor - Ulinastatin ( UTI) on the prevention of inflammatory mediators oxidative free radical production and changes in intestinal mucosa permeability in mini - pigs at early postburn stages. Methods Twelve Guizhou male mini - p...
Observation of the effect of hyperoxic sodium chloride solution on hypoxic injury
SUN Yong-hua, HU Xiaohua, CHEN Zhong, CHENG An-yuan, ZHONG Sui-hang
2003, 19(Z1): 22-26. doi: 10.3760/cma.j.issn.1009-2587.2003.Z1.110
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Objective To observe and explore the effects of compound hyperoxic sodium chloride solution on the management of burn shock. Methods (1) Wistar rats were randomly divided into 6 groups, i. e. A group (normal rats as control), B and C groups(the rats of 30% TBSA full thickness burn with compound sodi...
Experimental study on the proportion of three nutrients in burn rats with enteral nutrition
ZANG Jian, LU Shu-liang, LIAO Zhen-jiang, JIN Shu-wen, WANG Xin, IKEDA Shigeo, SAITO Hideaki, SHI Ji-xiang
2003, 19(Z1): 27-30. doi: 10.3760/cma.j.issn.1009-2587.2003.Z1.112
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Objective To observe the effect of alteration of proportion of carbohydrate, protein and fat intake on the metabolic level, immunological function and healing of the burn wound. Methods Twenty-one SD rats were inflicted with 30% TBSA scalding on the back after the gastrostomy was performed on them. ...
Preliminary observation of the effect of hyperoxic Ringer's solution on the patients with inhalation injury at early post-burn stage
JIA Chi-yu, HUANG Li-feng, CHEN Jian
2003, 19(Z1): 31-32. doi: 10.3760/cma.j.issn.1009-2587.2003.Z1.114
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Objective To investigate the clinical application of hyperoxic Ringers solution in the treatment of the burn patients with inhalation injury at the early postburn stage. Methods Eight patients with over 30% TBSA and moderate inhalation injury were randomly enrolled in the study ( + ), while other 4 ...
The therapeutic effect of early enteral nutrition togather with recombinant human growth hormone on severely scalded rats
GUO Guang-hua, WU Chou-lang, LI Guo-hui, YU Yu-rong, Cai Chen
2003, 19(Z1): 33-36. doi: 10.3760/cma.j.issn.1009-2587.2003.Z1.115
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Objective To evaluak the therapeutic effects of early enteral nutrition ( EEN ) togather with recombinant human growth hormone ( rhGH) on severely scalded rats. Methods One hundred and thirty Wistar rats were randomly divided into four groups, i. e. normal ( group N , n = 10) ,control( group C,n =40...
A reprot of 2-phase clinical trioe of Bing Shi Yu Shang ointment for the treatment of partial thickness burn -
HUANG Yue-sheng, SUN Yong-hua, XU Ming-da, ZHANG Zhen-xin, LI Xue-cheng, WANG Zhang-yang, PEN Yi-zhi, JIA Chi-yu, LUO Qi-zhi
2003, 19(Z1): 37-39. doi: 10.3760/cma.j.issn.1009-2587.2003.Z1.116
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Objective To observe the clinical effect and the safety of the Bing Shi Yu Shang ointment on the patients with partial thickness burn and residual wounds. Methods Two hundred patients were enrolled in the study and randomly divided into C ( 100 cases) and T groups( 100 cases) by the paralleled and s...
The effects of NO inhalation on cardice function in the burn patients with inhalation injury
Qi Shun-zhen, ZHAO Hong-liang, ZHAO Lian-kui, SUN Wei-hai
2003, 19(Z1): 40-43. doi: 10.3760/cma.j.issn.1009-2587.2003.Z1.117
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Objective To observe the effects of nitric oxide ( NO) inhalation on the cardiac function of the burn patients with inhalation injury. Methods Twelve burn patients with moderate degree of inhalation injury were enrolled in the study and randomly divided into control group ( C, six cases with convent...
Expression of some active peptides and extracellular matrix in the in vitro cultured tissue engineering skin
XIAO Shi-chu, XIA Zhao-fan, YANG Jun, LIU Zhi-guo, BEN Dao-feng, YU Wei-rong, YANG Yong, ZHU Shi-hui
2003, 19(Z1): 44-46. doi: 10.3760/cma.j.issn.1009-2587.2003.Z1.119
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Objective To investigate the bioactivity in the in vitro cultured tissue engineering skin. Methods Epithelial cells and fibroblasts were seeded onto the surface of an acellular dermal matrix to form a skin substitute, and the culture supernatants were collected on the 3rd and the 7th day. The change...
2003, 19(Z1): 10-10. doi: 10.3760/cma.j.issn.1009-2587.2003.Z1.104
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