2017 Vol. 33, No. 11

Expert Forum
Acute stress response after critical burn
Tang Hongtai, Zhu Feng
2017, 33(11): 657-659. doi: 10.3760/cma.j.issn.1009-2587.2017.11.001
Abstract:
The stress response is a preexisting and adaptive behavioral mode of all living beings, which may bring deleterious consequences of dysfunction or failure of tissue and organ. This article aims to elaborate theories of stress response, summarize the manifestation and mechanism of acute stress respon...
Burn Stress and Organ Damage
Establishment of myocardial targeted nanoparticles and preliminary evaluation of its effects on prevention and treatment of myocardial injury
Liu Yingying, Wang Chen, Luo Pengfei, Xia Zhaofan
2017, 33(11): 660-667. doi: 10.3760/cma.j.issn.1009-2587.2017.11.002
Abstract:
Objective To establish 3-{4-[2-hydroxyl-(1-methylethylamino) propoxy] phenyl} propionic acid cetylesters (PAC) modified nanoparticles, and preliminarily explore its cardiomyocyte-targeting function and protection effects on myocardium. Methods (1) HL-1 myocardial cells were divided into cyanidin-3 (...
Effects of astragalus polysaccharide on cardiac dysfunction in rabbits with severe scald injury
Zhong Lin, Zhan Jianhua, Luo Jinhua, Cheng Xing
2017, 33(11): 668-676. doi: 10.3760/cma.j.issn.1009-2587.2017.11.003
Abstract:
Objective To investigate the effects of astragalus polysaccharide (AP) on cardiac dysfunction in rabbits with severe scald injury. Methods Sixty-four New Zealand white rabbits were divided into pure scald group and AP group according to the random number table, with 32 rabbits in each group. Rabbits...
Effects of dexmedetomidine on myocardium of rats with severe burn at early stage
Wang Di, Yang Peilang, Zhang Xiong, Liu Yan
2017, 33(11): 677-681. doi: 10.3760/cma.j.issn.1009-2587.2017.11.004
Abstract:
Objective To investigate the effects of dexmedetomidine on myocardium of rats at early stage after severe burn. Methods Twenty specific pathogen free male SD rats were immersed in 90 ℃ hot water for 20 s, causing 30% total body surface area (TBSA) full-thickness scald (hereafter referred to as burn)...
Effects of hydrogen on the lung damage of mice at early stage of severe burn
Qin Chao, Bian Yingxue, Feng Tiantian, Zhang Jinhui, Yu Yonghao
2017, 33(11): 682-687. doi: 10.3760/cma.j.issn.1009-2587.2017.11.005
Abstract:
Objective To investigate the effects of hydrogen on the lung damage of mice at early stage of severe burn. Methods One hundred and sixty ICR mice were divided into sham injury, hydrogen, pure burn, and burn+ hydrogen groups according to the random number table, with 40 mice in each group. Mice in pu...
Effects of caspase-1 inhibitor VX765 on cold-restraint stress-induced acute gastric ulcer in mice
Zheng Shiqing, Hong Xudong, Chen Tiansheng, Luo Pengfei, Xiao Shichu
2017, 33(11): 688-693. doi: 10.3760/cma.j.issn.1009-2587.2017.11.006
Abstract:
Objective To investigate the protective effects of caspase-1 inhibitor VX765 on gastric mucosa of mice with cold-restraint stress-induced acute gastric ulcer. Methods Twenty-four specific pathogen free male C57BL/6J mice were divided into normal control group (NC), cold restrain group (CR), VX765 pr...
2017, 33(11): 676-676. doi: 10.3760/cma.j.issn.1009-2587.2017.11.101
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2017, 33(11): 687-687. doi: 10.3760/cma.j.issn.1009-2587.2017.11.102
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2017, 33(11): 699-702. doi: 10.3760/cma.j.issn.1009-2587.2017.11.008
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2017, 33(11): 702-704. doi: 10.3760/cma.j.issn.1009-2587.2017.11.009
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2017, 33(11): 705-707. doi: 10.3760/cma.j.issn.1009-2587.2017.11.010
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2017, 33(11): 708-711. doi: 10.3760/cma.j.issn.1009-2587.2017.11.011
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2017, 33(11): 711-713. doi: 10.3760/cma.j.issn.1009-2587.2017.11.012
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2017, 33(11): 713-713. doi: 10.3760/cma.j.issn.1009-2587.2017.11.103
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2017, 33(11): 714-715. doi: 10.3760/cma.j.issn.1009-2587.2017.11.013
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2017, 33(11): 715-715. doi: 10.3760/cma.j.issn.1009-2587.2017.11.104
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2017, 33(11): 716-717. doi: 10.3760/cma.j.issn.1009-2587.2017.11.014
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Original Article
Effects of endostatin pretreatment on fibrosis of human skin fibroblasts and the mechanisms
Ren Haitao, Li Yuan, Wang Shengdong, Han Chunmao
2017, 33(11): 694-698. doi: 10.3760/cma.j.issn.1009-2587.2017.11.007
Abstract:
Objective To explore the effects of endostatin pretreatment on fibrosis of human skin fibroblasts and the mechanisms. Methods Human skin fibroblasts were routinely cultured in vitro, and then the cells of passage 3 to 5 were used in the following experiments. The cells were divided into blank contro...
Review
Advances in the research of molecular mechanism of negative pressure wound therapy in improving wound healing
Liu Yang, Hu Dahai
2017, 33(11): 718-720. doi: 10.3760/cma.j.issn.1009-2587.2017.11.015
Abstract:
Recently, negative pressure wound therapy (NPWT) is a rising technology to improve wound healing. In clinical application, it benefits fast debridement and wound close, limits infection, and promotes wound healing. It is an effective therapy for all kinds of acute or chronic wound. Currently, resear...