Research advances on the mechanism of fractional laser in treating scars

Liu Huazhen; Lyu Kaiyang

doi:10.3760/cma.j.cn501120-20200315-00166

Volume 37 Issue 4

Apr. 2021

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Article Navigation > CHINESE JOURNAL OF BURNS AND WOUNDS > 2021 > 37(4): 386-390

Liu Huazhen, Lyu Kaiyang. Research advances on the mechanism of fractional laser in treating scars[J]. Chin j Burns, 2021, 37(4): 386-390. DOI: 10.3760/cma.j.cn501120-20200315-00166

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Liu Huazhen, Lyu Kaiyang. Research advances on the mechanism of fractional laser in treating scars[J]. Chin j Burns, 2021, 37(4): 386-390. DOI: 10.3760/cma.j.cn501120-20200315-00166

Citation:

Liu Huazhen, Lyu Kaiyang. Research advances on the mechanism of fractional laser in treating scars[J]. Chin j Burns, 2021, 37(4): 386-390. DOI: 10.3760/cma.j.cn501120-20200315-00166

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Research advances on the mechanism of fractional laser in treating scars

doi: 10.3760/cma.j.cn501120-20200315-00166

Department of Plastic Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China

Received Date: 2020-03-15
Available Online: 2021-10-28
Publish Date: 2021-04-20

Abstract

Abstract

Scars are the result of abnormal repair of skin tissue trauma. Recently, fractional laser is more and more widely used in the treatment of scars, but its mechanism is not clear. Studies have shown that fractional laser could produce multiple microthermal zones in target skin, induce wound repair responses, affect the function of epidermal and dermal cells, induce changes in blood vessels and collagens, and change the expression of heat shock proteins, microRNA, matrix metalloproteinases, cytokines such as transforming growth factor β, basic fibroblast growth factor, and facilitate drug delivery, thus achieving the effect of treating scars. This article reviews the mechanism of fractional laser in treating scars from three aspects, including the tissue and cell mechanism, molecular mechanism, and drug delivery.
- Cicatrix,
- Cytokines,
- Fractional laser,
- Molecular mechanisms

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Research advances on the mechanism of fractional laser in treating scars

doi: 10.3760/cma.j.cn501120-20200315-00166

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Research advances on the mechanism of fractional laser in treating scars

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