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Volume 37 Issue 10
Oct.  2021
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Article Navigation >  CHINESE JOURNAL OF BURNS AND WOUNDS  > 2021  >  37(10): 990-995
Li YL,Chen N,Xie WG.Research advances on the application of platelet concentrate products in wound repair[J].Chin J Burns,2021,37(10):990-995.DOI: 10.3760/cma.j.cn501120-20200730-00363.
Citation: Li YL,Chen N,Xie WG.Research advances on the application of platelet concentrate products in wound repair[J].Chin J Burns,2021,37(10):990-995.DOI: 10.3760/cma.j.cn501120-20200730-00363.
shu

Research advances on the application of platelet concentrate products in wound repair

doi: 10.3760/cma.j.cn501120-20200730-00363

  • Institute of Burns, Tongren Hospital of Wuhan University & Wuhan Third Hospital, Wuhan 430060, China

Funds:

General Program of National Natural Science Foundation of China 81772097

Action Plan for Science and Technology in Major Disease Prevention and Control 2018-ZX-01S-001

More Information
  • Corresponding author: Xie Weiguo, Email: wgxie@hotmail.com
  • Received Date: 2020-07-30
    Abstract
  • Multiple growth factors are required to regulate the wound repair process. Currently, there is still a lack of potent, durable, and inexpensive growth factor product in clinical practice. Meanwhile, platelet concentrate products provide an economical, convenient, and effective choice for the treatment of wounds in clinical practice. Starting from the first generation of platelet concentrate products, platelet-rich plasma, researchers have focused on optimizing the performance of platelet concentrate products for higher stability, more abundant bioactive factors, and more optimal clinical performance. Platelet-rich fibrin and concentrated growth factor emerged since then. Platelet concentrate products have the effect of promoting the speed of wound healing and enhancing the quality. This article aims to summarize the history and classification of platelet concentrate products, compare their properties and clinical applications, elaborate their mechanism of action, and analyze the problems existing in relevant researches while prospecting the future development of this field.

     

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