Email Alerts
RSS
Volume 38 Issue 6
Jun.  2022
Turn off MathJax
Article Contents
Article Navigation >  CHINESE JOURNAL OF BURNS AND WOUNDS  > 2022  >  38(6): 532-537
Dai JJ,Wang L,Qiu HY,et al.Clinical effects of autologous follicular unit extraction transplantation in the treatment of small area secondary cicatricial alopecia after burns[J].Chin J Burns Wounds,2022,38(6):532-537.DOI: 10.3760/cma.j.cn501120-20210224-00064.
Citation: Dai JJ,Wang L,Qiu HY,et al.Clinical effects of autologous follicular unit extraction transplantation in the treatment of small area secondary cicatricial alopecia after burns[J].Chin J Burns Wounds,2022,38(6):532-537.DOI: 10.3760/cma.j.cn501120-20210224-00064.
shu

Clinical effects of autologous follicular unit extraction transplantation in the treatment of small area secondary cicatricial alopecia after burns

doi: 10.3760/cma.j.cn501120-20210224-00064

  • Department of Burns and Cutaneous Surgery, Burn Center of PLA, the First Affiliated Hospital of Air Force Medical University, Xi'an 710032, China

Funds:

Emergency Management Project of National Natural Science Foundation of China 81741105

Industry-University-Research Innovation Fund of the Science and Technology Development Center of the Ministry of Education of China 2021JH030

More Information
    Abstract
  •   Objective  To explore the clinical effects of autologous follicular unit extraction (FUE) transplantation in the treatment of small area secondary cicatricial alopecia (hereinafter referred to as cicatricial alopecia) after burns.  Methods  A retrospective observational study was carried out. According to the adopted treatment methods, 18 patients (12 males and 6 females, aged (29±6) years) who received autologous FUE transplantation for small area cicatricial alopecia after burns from March 2017 to November 2019 in the First Affiliated Hospital of Air Force Medical University were included in FUE transplantation group, and 18 patients (13 males and 5 females, aged (33±5) years) who were treated with expanded flap transplantation for small area cicatricial alopecia after burns by the same surgery team during the same period in the same hospital were included in expanded flap transplantation group. All the patients were followed up for more than 1 year. At the last follow-up, the follicular unit density in the transplanted area was measured by Folliscope hair detection system and the hair survival rate was calculated; the visual analogue scale (VAS) method was adopted to evaluate the treatment effect; patients were asked their satisfaction with the treatment effect and the occurrence of complications during follow-up; the hair growth and the scalp thickness, pain, pruritus, pigmentation, and surface roughness of the transplanted area were recorded. Data were statistically analyzed with Fisher's exact probability test and independent sample t test.  Results  At the last follow-up, the follicular unit density in the transplanted area of patients in FUE transplantation group was (46.8±2.0)/cm2, which was significantly higher than (42.5±4.3)/cm2 in expanded flap transplantation group (t=3.84, P<0.01); the hair survival rates of patients were similar between the two groups (P>0.05). At the last follow-up, VAS scores evaluating the treatment effect of patients were similar between the two groups (P>0.05); the satisfaction score of patients toward the treatment effect in FUE transplantation group was 8.6±1.1, which was significantly higher than 7.6±0.8 in expanded flap transplantation group (t=2.89, P<0.01). During the follow-up, no inflammation or infection occurred in patients of the two groups, but only 2 patients in expanded flap transplantation group had postoperative pain. At the last follow-up, the transplanted area of patients in the two groups was covered with new hair, and the hair growth direction was basically consistent with the surrounding normal hair; scalp thickness, pain, pruritus, pigmentation, and surface roughness of the transplanted area of patients were similar between the two groups (P>0.05).  Conclusions  Autologous FUE transplantation has better long-term follicular unit density and patients' satisfaction than expanded flap transplantation in the treatment of small area cicatricial alopecia after burns, showing better postoperative effect and a good prospect of clinical application.

     

    • FullText(HTML)
  • loading
    • References(33)
  • [1]
    AhmadM. Alopecia[M]. London: IntechOpen,2018:89-111.
    [2]
    YooH,MohJ,ParkJU.Treatment of postsurgical scalp scar deformity using follicular unit hair transplantation[J].Biomed Res Int,2019,2019:3423657.DOI: 10.1155/2019/3423657.
    [3]
    张家平,袁希,江旭品,等.基于“MRIS”原则采用扩张皮瓣美学整复颏颈部瘢痕挛缩畸形[J].中华烧伤与创面修复杂志,2022,38(4):306-312.DOI: 10.3760/cma.j.cn501120-20211130-00401.
    [4]
    王光华,卫伟,卢雪涛.扩张器在修复瘢痕性秃发中的应用[J].中国美容整形外科杂志,2017,28(7):431-432,435.DOI: 10.3969/j.issn.1673-7040.2017.07.017.
    [5]
    李长青,韩颖,郑建中.扩张皮瓣修复瘢痕性秃发的临床效果[J].中华医学美学美容杂志,2015,21(3):178-179.DOI: 10.3760/cma.j.issn.1671-0290.2015.03.016.
    [6]
    OgawaR. Surgery for scar revision and reduction: from primary closure to flap surgery[J/OL]. Burns Trauma,2019,7:7[2022-02-10].https://pubmed. ncbi.nlm.nih.gov/30891462/.DOI: 10.1186/s41038-019-0144-5.
    [7]
    张菊芳,沈海燕,韩蕾,等.高密度毛发移植术在瘢痕性脱发治疗中的应用[J].中国美容整形外科杂志,2011,22(7):388-390.DOI: 10.3969/j.issn.1673-7040.2011.07.002.
    [8]
    田治国,杨云蔚,陈立,等.毛囊单位抽取术治疗头皮短小瘢痕毛发缺损[J].中华整形外科杂志,2016,32(3):229-230.DOI: 10.3760/cma.j.issn.1009-4598.2016.03.017.
    [9]
    蒋文杰,王梦,王博,等.毛囊取出移位种植矫正瘢痕性秃发术后毛发方向错乱[J].中华整形外科杂志,2020,36(10):1085-1087.DOI: 10.3760/cma.j.cn114453-20200613-00362.
    [10]
    蒋文杰,赵永刚,成倩秋,等.扩张头皮皮瓣与毛发移植修复鬓角缺损的临床效果[J].中华医学美学美容杂志,2016,22(5):274-276.DOI: 10.3760/cma.j.issn.1671-0290.2016.05.006.
    [11]
    贺苏,于杰,艾岩岩.整形美容手术患者的心理分析及护理方法研究[J].中国医疗美容,2017,7(5):72-74.DOI: 10.19593/j.issn.2095-0721.2017.05.027.
    [12]
    JungS,OhSJ,Hoon KohS.Hair follicle transplantation on scar tissue[J].J Craniofac Surg,2013,24(4):1239-1241.DOI: 10.1097/SCS.0b013e31828a78ad.
    [13]
    LeeBS,ChanJY,MonseliseA,et al.Assessment of hair density and caliber in Caucasian and Asian female subjects with female pattern hair loss by using the Folliscope[J].J Am Acad Dermatol,2012,66(1):166-167.DOI: 10.1016/j.jaad.2011.04.023.
    [14]
    ReipsUD,FunkeF.Interval-level measurement with visual analogue scales in internet-based research: VAS Generator[J].Behav Res Methods,2008,40(3):699-704.DOI: 10.3758/brm.40.3.699.
    [15]
    王志军,刘林嶓.美容外科学[M].北京:人民卫生出版社,2012:67.
    [16]
    马显杰,李威扬,刘超华,等.面部烧伤后瘢痕的美学整复策略及疗效[J].中华烧伤杂志,2016,32(8):469-473.DOI: 10.3760/cma.j.issn.1009-2587.2016.08.006.
    [17]
    刘家祺,何安琪,杨燕文,等.毛囊单位移植在皮肤创面修复中的应用[J].中国美容医学,2018,27(2):15-18.
    [18]
    ShaoH,HuH, JinY,et al.Follicular unit transplantation for the treatment of secondary cicatricial alopecia[J].Plast Surg (Oakv),2014,22(4):249-253.DOI: 10.4172/plastic-surgery.1000885.
    [19]
    杨青,薛萍,窦文婕,等.毛囊单位提取移植术联合重组牛碱性成纤维细胞生长因子以及米诺地尔治疗继发性瘢痕秃发的临床效果[J].中华烧伤杂志,2021,37(8):718-724.DOI: 10.3760/cma.j.cn501120-20210416-00132.
    [20]
    祝飞,张菊芳,刘筱雯,等.自体毛囊单位提取技术在瘢痕性秃发中的应用[J].中国美容整形外科杂志,2017,28(9):523-524,528.DOI: 10.3969/j.issn.1673-7040.2017.09.004.
    [21]
    张伟,陈莹,王芳,等.毛囊单位提取移植术治疗瘢痕性秃发的临床应用和疗效观察[J].中华烧伤杂志,2021,37(5):469-474.DOI: 10.3760/cma.j.cn501120-20200315-00170.
    [22]
    SharmaR,RanjanA.Follicular unit extraction (FUE) hair transplant: curves ahead[J].J Maxillofac Oral Surg,2019,18(4):509-517.DOI: 10.1007/s12663-019-01245-6.
    [23]
    VasudevanB,NeemaS,GhoshK,et al.Hair transplantation by follicular unit extraction for male androgenetic alopecia: a retrospective observational study from two centers[J].Med J Armed Forces India,2020,76(4):430-437.DOI: 10.1016/j.mjafi.2019.11.001.
    [24]
    PangtiR,GuptaV,GuptaS.Follicular unit extraction of leukotrichia and replacement with follicular units from scalp in combination with epidermal cell suspension in a case of vitiligo[J].Dermatol Ther,2020,33(6):e13916.DOI: 10.1111/dth.13916.
    [25]
    田子红,徐华飞,田治国.毛囊单位提取术治疗发际缘不同类型瘢痕性秃发临床观察[J].中华皮肤科杂志,2017,50(12):923-925.DOI: 10.3760/cma.j.issn.0412-4030.2017.12.017.
    [26]
    BarrL,BarreraA.Use of hair grafting in scar camouflage[J].Facial Plast Surg Clin North Am,2011,19(3):559-568.DOI: 10.1016/j.fsc.2011.06.010.
    [27]
    GargAK,GargS.Donor harvesting: follicular unit excision[J].J Cutan Aesthet Surg,2018,11(4):195-201.DOI: 10.4103/JCAS.JCAS_123_18.
    [28]
    Humayun MohmandM,AhmadM.Effect of follicular unit extraction on the donor area[J].World J Plast Surg,2018,7(2):193-197.
    [29]
    KerureAS,AgrawalS,DhuratR,et al.Using the combination of the Kerure clamp and serrated punch to decrease the transection rate in follicular unit extraction (FUE)[J/OL].J Am Acad Dermatol,2019:S0190-9622(19)32439-9(2019-07-24)[2021-02- 24].https://pubmed.ncbi.nlm.nih.gov/31351095/.DOI:10.1016/j.jaad.2019.07.056.[publised online ahead of print].
    [30]
    NakatsuiT,WongJ,GrootD.Survival of densely packed follicular unit grafts using the lateral slit technique[J].Dermatol Surg,2008,34(8):1016-1022; discussion 1022-1025.DOI: 10.1111/j.1524-4725.2008.34200.x.
    [31]
    张春韶广东健康成年人头发密度及其与中医体质的关系广州广州中医药大学2014

    张春韶.广东健康成年人头发密度及其与中医体质的关系[D].广州:广州中医药大学,2014.
    [32]
    EpsteinGK,EpsteinJ,NikolicJ.Follicular unit excision: current practice and future developments[J].Facial Plast Surg Clin North Am,2020,28(2):169-176.DOI: 10.1016/j.fsc.2020.01.006.
    [33]
    OrsS,OzkoseM,OrsS.Follicular unit extraction hair transplantation with micromotor: eight years experience[J].Aesthetic Plast Surg,2015,39(4):589-596.DOI: 10.1007/s00266-015-0494-8.
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(2)  / Tables(2)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (247) PDF downloads(31) Cited by()
    Proportional views
    Related

    Copyright © Chinese Journal of Burns京ICP备07035254号-14

    E-mail：shaoshangzazhi@163.com

    Website：https://zhsszz.xml-journal.net/

    Supported by: Beijing Renhe Information Technology Co. Ltd    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return