| Citation: | Wang LX,Li YP,Wu SM,et al.Research progress on the role of adipose-derived stem cell exosomes in skin scar formation[J].Chin J Burns Wounds,2023,39(3):295-300.DOI: 10.3760/cma.j.cn501225-20220308-00057.
|
| [1] |
OjehN,BharathaA,GaurU,et al.Keloids: current and emerging therapies[J].Scars Burn Heal,2020,6:2059513120940499.DOI: 10.1177/2059513120940499.
|
| [2] |
中国整形美容协会瘢痕医学分会.瘢痕早期治疗全国专家共识(2020版)[J].中华烧伤杂志,2021,37(2):113-125.DOI: 10.3760/cma.j.cn501120-20200609-00300.
|
| [3] |
LouP,LiuS,XuX,et al.Extracellular vesicle-based therapeutics for the regeneration of chronic wounds: current knowledge and future perspectives[J].Acta Biomater,2021,119:42-56.DOI: 10.1016/j.actbio.2020.11.001.
|
| [4] |
DoyleLM,WangMZ.Overview of extracellular vesicles, their origin, composition, purpose, and methods for exosome isolation and analysis[J].Cells,2019,8(7):727.DOI: 10.3390/cells8070727.
|
| [5] |
MaasS,BreakefieldXO,WeaverAM.Extracellular vesicles: unique intercellular delivery vehicles[J].Trends Cell Biol,2017,27(3):172-188.DOI: 10.1016/j.tcb.2016.11.003.
|
| [6] |
JuanT,FürthauerM.Biogenesis and function of ESCRT-dependent extracellular vesicles[J].Semin Cell Dev Biol,2018,74:66-77.DOI: 10.1016/j.semcdb.2017.08.022.
|
| [7] |
CabralJ,RyanAE,GriffinMD,et al.Extracellular vesicles as modulators of wound healing[J].Adv Drug Deliv Rev,2018,129:394-406.DOI: 10.1016/j.addr.2018.01.018.
|
| [8] |
SabolRA,BowlesAC,CôtéA,et al.Therapeutic potential of adipose stem cells[J].Adv Exp Med Biol,2021,1341:15-25.DOI: 10.1007/5584_2018_248.
|
| [9] |
O'BrienK,BreyneK,UghettoS,et al.RNA delivery by extracellular vesicles in mammalian cells and its applications[J].Nat Rev Mol Cell Biol,2020,21(10):585-606.DOI: 10.1038/s41580-020-0251-y.
|
| [10] |
GurungS,PerocheauD,TouramanidouL,et al.The exosome journey: from biogenesis to uptake and intracellular signalling[J].Cell Commun Signal,2021,19(1):47.DOI: 10.1186/s12964-021-00730-1.
|
| [11] |
ReinkeJM,SorgH.Wound repair and regeneration[J].Eur Surg Res,2012,49(1):35-43.DOI: 10.1159/000339613.
|
| [12] |
RippaAL,KalabushevaEP,VorotelyakEA.Regeneration of dermis: scarring and cells involved[J].Cells,2019,8(6):607.DOI: 10.3390/cells8060607.
|
| [13] |
WangZC,ZhaoWY,CaoY,et al.The roles of inflammation in keloid and hypertrophic scars[J].Front Immunol,2020,11:603187.DOI: 10.3389/fimmu.2020.603187.
|
| [14] |
YangJ,LiS,HeL,et al.Adipose-derived stem cells inhibit dermal fibroblast growth and induce apoptosis in keloids through the arachidonic acid-derived cyclooxygenase-2/prostaglandin E2 cascade by paracrine[J/OL].Burns Trauma,2021,9:tkab020[2022-03-08].https://pubmed.ncbi.nlm.nih.gov/34514006/.DOI: 10.1093/burnst/tkab020.
|
| [15] |
Abdu AllahAMK,MohammedKI,FaragAGA,et al.Interleukin-6 serum level and gene polymorphism in keloid patients[J].Cell Mol Biol (Noisy-le-grand),2019,65(5):43-48.
|
| [16] |
ChenZ,GaoZ,XiaL,et al.Dysregulation of DPP4-CXCL12 balance by TGF-β1/SMAD pathway promotes CXCR4+ inflammatory cell infiltration in keloid scars[J].J Inflamm Res,2021,14:4169-4180.DOI: 10.2147/JIR.S326385.
|
| [17] |
ChenZ,WangZ,JinT,et al.Fibrogenic fibroblast-selective near-infrared phototherapy to control scarring[J].Theranostics,2019,9(23):6797-6808.DOI: 10.7150/thno.36375.
|
| [18] |
ZhuZ,HouQ,LiM,et al.Molecular mechanism of myofibroblast formation and strategies for clinical drugs treatments in hypertrophic scars[J].J Cell Physiol,2020,235(5):4109-4119.DOI: 10.1002/jcp.29302.
|
| [19] |
HsuCK,LinHH,HarnHI,et al.Caveolin-1 controls hyperresponsiveness to mechanical stimuli and fibrogenesis-associated RUNX2 activation in keloid fibroblasts[J].J Invest Dermatol,2018,138(1):208-218.DOI: 10.1016/j.jid.2017.05.041.
|
| [20] |
YinJL,WuY,YuanZW,et al.Advances in scarless foetal wound healing and prospects for scar reduction in adults[J].Cell Prolif,2020,53(11):e12916.DOI: 10.1111/cpr.12916.
|
| [21] |
LeungA,CrombleholmeTM,KeswaniSG.Fetal wound healing: implications for minimal scar formation[J].Curr Opin Pediatr,2012,24(3):371-378.DOI: 10.1097/MOP.0b013e3283535790.
|
| [22] |
KavasiRM,BerdiakiA,SpyridakiI,et al.HA metabolism in skin homeostasis and inflammatory disease[J].Food Chem Toxicol,2017,101:128-138.DOI: 10.1016/j.fct.2017.01.012.
|
| [23] |
IlieșRF,AioaneiCS,CătanăA,et al.Involvement of COL5A2 and TGF-β1 in pathological scarring[J].Exp Ther Med,2021,22(4):1067.DOI: 10.3892/etm.2021.10501.
|
| [24] |
YuanR,DaiX,LiY,et al.Exosomes from miR-29a-modified adipose-derived mesenchymal stem cells reduce excessive scar formation by inhibiting TGF-β2/Smad3 signaling[J].Mol Med Rep,2021,24(5):758.DOI: 10.3892/mmr.2021.12398.
|
| [25] |
LichtmanMK,Otero-VinasM,FalangaV.Transforming growth factor beta (TGF-β) isoforms in wound healing and fibrosis[J].Wound Repair Regen,2016,24(2):215-222.DOI: 10.1111/wrr.12398.
|
| [26] |
WalravenM,TalhoutW,BeelenRH,et al.Healthy human second-trimester fetal skin is deficient in leukocytes and associated homing chemokines[J].Wound Repair Regen,2016,24(3):533-541.DOI: 10.1111/wrr.12421.
|
| [27] |
MascharakS,desJardins-ParkHE,DavittMF,et al.Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring[J].Science,2021,372(6540):eaba2374.DOI: 10.1126/science.aba2374.
|
| [28] |
XuX, GuS, HuangX, et al. The role of macrophages in the formation of hypertrophic scars and keloids[J/OL]. Burns Trauma, 2020,8:tkaa006[2022-03-08]. https://pubmed.ncbi.nlm.nih.gov/32341919/.DOI: 10.1093/burnst/tkaa006.
|
| [29] |
HeoJS,ChoiY,KimHO.Adipose-derived mesenchymal stem cells promote M2 macrophage phenotype through exosomes[J].Stem Cells Int,2019,2019:7921760.DOI: 10.1155/2019/7921760.
|
| [30] |
DomenisR,CifùA,QuagliaS,et al.Pro inflammatory stimuli enhance the immunosuppressive functions of adipose mesenchymal stem cells-derived exosomes[J].Sci Rep,2018,8(1):13325.DOI: 10.1038/s41598-018-31707-9.
|
| [31] |
BlazquezR,Sanchez-MargalloFM,de la RosaO,et al.Immunomodulatory potential of human adipose mesenchymal stem cells derived exosomes on in vitro stimulated T cells[J].Front Immunol,2014,5:556.DOI: 10.3389/fimmu.2014.00556.
|
| [32] |
MaX,ChenJ,XuB,et al.Keloid-derived keratinocytes acquire a fibroblast-like appearance and an enhanced invasive capacity in a hypoxic microenvironment in vitro[J].Int J Mol Med,2015,35(5):1246-1256.DOI: 10.3892/ijmm.2015.2135.
|
| [33] |
BaiY,HanYD,YanXL,et al.Adipose mesenchymal stem cell-derived exosomes stimulated by hydrogen peroxide enhanced skin flap recovery in ischemia-reperfusion injury[J].Biochem Biophys Res Commun,2018,500(2):310-317.DOI: 10.1016/j.bbrc.2018.04.065.
|
| [34] |
LiangX,ZhangL,WangS,et al.Exosomes secreted by mesenchymal stem cells promote endothelial cell angiogenesis by transferring miR-125a[J].J Cell Sci,2016,129(11):2182-2189.DOI: 10.1242/jcs.170373.
|
| [35] |
LiY,ZhangJ,ShiJ,et al.Exosomes derived from human adipose mesenchymal stem cells attenuate hypertrophic scar fibrosis by miR-192-5p/IL-17RA/Smad axis[J].Stem Cell Res Ther,2021,12(1):221.DOI: 10.1186/s13287-021-02290-0.
|
| [36] |
WangL,HuL,ZhouX,et al.Exosomes secreted by human adipose mesenchymal stem cells promote scarless cutaneous repair by regulating extracellular matrix remodelling[J].Sci Rep,2017,7(1):13321.DOI: 10.1038/s41598-017-12919-x.
|
| [37] |
LiuJ,LiF,LiuB,et al.Adipose-derived mesenchymal stem cell exosomes inhibit transforming growth factor-β1-induced collagen synthesis in oral mucosal fibroblasts[J].Exp Ther Med,2021,22(6):1419.DOI: 10.3892/etm.2021.10854.
|
| [38] |
LiX,WangY,ShiL,et al.Magnetic targeting enhances the cutaneous wound healing effects of human mesenchymal stem cell-derived iron oxide exosomes[J].J Nanobiotechnology,2020,18(1):113.DOI: 10.1186/s12951-020-00670-x.
|
| [39] |
WangC,WangM,XuT,et al.Engineering bioactive self-healing antibacterial exosomes hydrogel for promoting chronic diabetic wound healing and complete skin regeneration[J].Theranostics,2019,9(1):65-76.DOI: 10.7150/thno.29766.
|
| [40] |
WangM,WangC,ChenM,et al.Efficient angiogenesis-based diabetic wound healing/skin reconstruction through bioactive antibacterial adhesive ultraviolet shielding nanodressing with exosome release[J].ACS Nano,2019,13(9):10279-10293.DOI: 10.1021/acsnano.9b03656.
|
| [41] |
ZhaoD,YuZ,LiY,et al.GelMA combined with sustained release of HUVECs derived exosomes for promoting cutaneous wound healing and facilitating skin regeneration[J].J Mol Histol,2020,51(3):251-263.DOI: 10.1007/s10735-020-09877-6.
|
| [42] |
SafariB,AghazadehM,DavaranS,et al.Exosome-loaded hydrogels: a new cell-free therapeutic approach for skin regeneration[J].Eur J Pharm Biopharm,2022,171:50-59.DOI: 10.1016/j.ejpb.2021.11.002.
|
| [43] |
ElsharkasyOM,NordinJZ,HageyDW,et al.Extracellular vesicles as drug delivery systems: why and how?[J].Adv Drug Deliv Rev,2020,159:332-343.DOI: 10.1016/j.addr.2020.04.004.
|
| [44] |
LvQ, DengJ, ChenY, et al. Engineered human adipose stem-cell-derived exosomes loaded with miR-21-5p to promote diabetic cutaneous wound healing[J]. Mol Pharm, 2020,17(5):1723-1733.DOI: 10.1021/acs.molpharmaceut.0c00177.
|
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Wang LX,Li YP,Wu SM,et al.Research progress on the role of adipose-derived stem cell exosomes in skin scar formation[J].Chin J Burns Wounds,2023,39(3):295-300.DOI: 10.3760/cma.j.cn501225-20220308-00057.
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