Volume 38 Issue 10
Oct.  2022
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Chen JQ,Zhu SH.Research advances on the construction of artificial dermal scaffolds based on biomaterials[J].Chin J Burns Wounds,2022,38(10):968-972.DOI: 10.3760/cma.j.cn501225-20220606-00221.
Citation: Chen JQ,Zhu SH.Research advances on the construction of artificial dermal scaffolds based on biomaterials[J].Chin J Burns Wounds,2022,38(10):968-972.DOI: 10.3760/cma.j.cn501225-20220606-00221.

Research advances on the construction of artificial dermal scaffolds based on biomaterials

doi: 10.3760/cma.j.cn501225-20220606-00221
Funds:

National Key Research and Development Program of China 2019YFA0110603

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  • Corresponding author: Zhu Shihui, Email: doctorzhushihui@163.com
  • Received Date: 2022-06-06
    Available Online: 2022-10-24
  • In the field of wound repair, scarless healing and complete reconstruction of skin function are major challenges in clinical and basic research. At present, a variety of artificial dermal scaffolds have been used in the clinical repair of wounds to overcome the problems such as skin structural disorders caused by tissue defects. The biomaterials used to make artificial dermal scaffolds in skin and tissue engineering research mainly include three categories: natural biomaterials, biosynthetic materials, and organic polymer materials. This review summarizes the biocompatibility, bioactivity, and degradability of biomaterials and their effects on wound healing, and provides an overview of artificial dermal scaffold construction strategies based on biomaterials, wound healing cells, and associated cytokines.

     

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  • [1]
    中国老年医学学会烧创伤分会.天然真皮基质应用于创面修复的全国专家共识(2020版)[J].中华烧伤杂志,2020,36(10):895-900.DOI: 10.3760/cma.j.cn501120-20200308-00134.
    [2]
    Rahmani Del BakhshayeshA,AnnabiN,KhalilovR,et al.Recent advances on biomedical applications of scaffolds in wound healing and dermal tissue engineering[J].Artif Cells Nanomed Biotechnol,2018,46(4):691-705.DOI: 10.1080/21691401.2017.1349778.
    [3]
    CrawfordL,WyattM,BryersJ,et al.Biocompatibility evolves: phenomenology to toxicology to regeneration[J].Adv Healthc Mater,2021,10(11):e2002153.DOI: 10.1002/adhm.202002153.
    [4]
    SunG.Pro-regenerative hydrogel restores scarless skin during cutaneous wound healing[J].Adv Healthc Mater,2017,6(23):1700659.DOI: 10.1002/adhm.201700659.
    [5]
    LiY,XiaoY,LiuC.The horizon of materiobiology: a perspective on material-guided cell behaviors and tissue engineering[J].Chem Rev,2017,117(5):4376-4421.DOI: 10.1021/acs.chemrev.6b00654.
    [6]
    IorioV,TroughtonLD,HamillKJ.Laminins: roles and utility in wound repair[J].Adv Wound Care (New Rochelle),2015,4(4):250-263.DOI: 10.1089/wound.2014.0533.
    [7]
    KangHW,LeeSJ,KoIK,et al.A 3D bioprinting system to produce human-scale tissue constructs with structural integrity[J].Nat Biotechnol,2016,34(3):312-319.DOI: 10.1038/nbt.3413.
    [8]
    HassanAA,RadwanHA,AbdelaalSA,et al.Polycaprolactone based electrospun matrices loaded with Ag/hydroxyapatite as wound dressings: morphology, cell adhesion, and antibacterial activity[J].Int J Pharm,2021,593:120143.DOI: 10.1016/j.ijpharm.2020.120143.
    [9]
    WeiS,XuP,YaoZ,et al.A composite hydrogel with co-delivery of antimicrobial peptides and platelet-rich plasma to enhance healing of infected wounds in diabetes[J].Acta Biomater,2021,124:205-218.DOI: 10.1016/j.actbio.2021.01.046.
    [10]
    中国老年医学学会烧创伤分会.胶原类创面材料临床应用全国专家共识(2018版)[J].中华烧伤杂志,2018,34(11):766-769.DOI: 10.3760/cma.j.issn.1009-2587.2018.11.009.
    [11]
    HosseiniM,MozafariM.Cerium oxide nanoparticles: recent advances in tissue engineering[J].Materials (Basel),2020,13(14):3072.DOI: 10.3390/ma13143072.
    [12]
    FukanoY,UsuiML,UnderwoodRA,et al.Epidermal and dermal integration into sphere-templated porous poly(2-hydroxyethyl methacrylate) implants in mice[J].J Biomed Mater Res A,2010,94(4):1172-1186.DOI: 10.1002/jbm.a.32798.
    [13]
    ShevchenkoRV,EemanM,RowshanravanB,et al.The in vitro characterization of a gelatin scaffold, prepared by cryogelation and assessed in vivo as a dermal replacement in wound repair[J].Acta Biomater,2014,10(7):3156-3166.DOI: 10.1016/j.actbio.2014.03.027.
    [14]
    HuY,WangJ,LiX,et al.Facile preparation of bioactive nanoparticle/poly(ε-caprolactone) hierarchical porous scaffolds via 3D printing of high internal phase Pickering emulsions[J].J Colloid Interface Sci,2019,545:104-115.DOI: 10.1016/j.jcis.2019.03.024.
    [15]
    YangY,RitchieAC,EverittNM.Using type III recombinant human collagen to construct a series of highly porous scaffolds for tissue regeneration[J].Colloids Surf B Biointerfaces,2021,208:112139.DOI: 10.1016/j.colsurfb.2021.112139.
    [16]
    QaziTH,TytgatL,DubruelP,et al.Extrusion printed scaffolds with varying pore size as modulators of MSC angiogenic paracrine effects[J].ACS Biomater Sci Eng,2019,5(10):5348-5358.DOI: 10.1021/acsbiomaterials.9b00843.
    [17]
    ChoiDJ,ParkS,GuKB,et al.Effect of the pore size in a 3D bioprinted gelatin scaffold on fibroblast proliferation[J].Journal of Industrial and Engineering Chemistry,2018:S1226086X18303952.DOI: 10.1016/j.jiec.2018.07.013.
    [18]
    XiaH,ChenQ,FangY,et al.Directed neurite growth of rat dorsal root ganglion neurons and increased colocalization with Schwann cells on aligned poly(methyl methacrylate) electrospun nanofibers[J].Brain Res,2014,1565:18-27.DOI: 10.1016/j.brainres.2014.04.002.
    [19]
    HejazianLB,EsmaeilzadeB,Moghanni GhoroghiF,et al.The role of biodegradable engineered nanofiber scaffolds seeded with hair follicle stem cells for tissue engineering[J].Iran Biomed J,2012,16(4):193-201.
    [20]
    FengB,DuanH,FuW,et al.Effect of inhomogeneity of the electrospun fibrous scaffolds of gelatin/polycaprolactone hybrid on cell proliferation[J].J Biomed Mater Res A,2015,103(2):431-438.DOI: 10.1002/jbm.a.35184.
    [21]
    TamayolA,AkbariM,AnnabiN,et al.Fiber-based tissue engineering: progress, challenges, and opportunities[J].Biotechnol Adv,2013,31(5):669-687.DOI: 10.1016/j.biotechadv.2012.11.007.
    [22]
    FreemanR,HanM,ÁlvarezZ,et al.Reversible self-assembly of superstructured networks[J].Science,2018,362(6416):808-813.DOI: 10.1126/science.aat6141.
    [23]
    NorouziM,BoroujeniSM,OmidvarkordshouliN,et al.Advances in skin regeneration: application of electrospun scaffolds[J].Adv Healthc Mater,2015,4(8):1114-1133.DOI: 10.1002/adhm.201500001.
    [24]
    ShevchenkoRV,EemanM,RowshanravanB,et al.The in vitro characterization of a gelatin scaffold, prepared by cryogelation and assessed in vivo as a dermal replacement in wound repair[J].Acta Biomater,2014,10(7):3156-3166.DOI: 10.1016/j.actbio.2014.03.027.
    [25]
    SampsonSL,SaraivaL,GustafssonK,et al.Cell electrospinning: an in vitro and in vivo study[J].Small,2014,10(1):78-82.DOI: 10.1002/smll.201300804.
    [26]
    KhandakerM,NomhwangeH,ProgriH,et al.Evaluation of polycaprolactone electrospun nanofiber-composites for artificial skin based on dermal fibroblast culture[J].Bioengineering (Basel),2022,9(1):19.DOI: 10.3390/bioengineering9010019.
    [27]
    AmirsadeghiA,KhorramM,HashemiSS.Preparation of multilayer electrospun nanofibrous scaffolds containing soluble eggshell membrane as potential dermal substitute[J].J Biomed Mater Res A,2021,109(10):1812-1827.DOI: 10.1002/jbm.a.37174.
    [28]
    DhandayuthapaniB,YoshidaY,MaekawaT,et al.Polymeric scaffolds in tissue engineering application: a review[J].International Journal of Polymer Science,2011:609-618.DOI: 10.1155/2011/290602.
    [29]
    GilmartinDJ,AlexalineMM,ThrasivoulouC,et al.Integration of scaffolds into full-thickness skin wounds: the connexin response[J].Adv Healthc Mater,2013,2(8):1151-1160.DOI: 10.1002/adhm.201200357.
    [30]
    GleadallA,VisscherD,YangJ,et al.Review of additive manufactured tissue engineering scaffolds: relationship between geometry and performance[J/OL].Burns Trauma,2018,6:19[2022-06-06]. https://pubmed.ncbi.nlm.nih.gov/29988731/.DOI: 10.1186/s41038-018-0121-4.
    [31]
    盛嘉隽,刘功成,李海航,等.皮肤三维打印的研究进展[J].中华烧伤杂志,2017,33(1):27-30.DOI: 10.3760/cma.j.issn.1009-2587.2017.01.007.
    [32]
    ShafieeA.Design and fabrication of three-dimensional printed scaffolds for cancer precision medicine[J].Tissue Eng Part A,2020,26(5/6):305-317.DOI: 10.1089/ten.TEA.2019.0278.
    [33]
    DattaP,DhawanA,YuY,et al.Bioprinting of osteochondral tissues: a perspective on current gaps and future trends[J].Int J Bioprint,2017,3(2):007.DOI: 10.18063/IJB.2017.02.007.
    [34]
    ShieMY,LeeJJ,HoCC,et al.Effects of gelatin methacrylate bio-ink concentration on mechano-physical properties and human dermal fibroblast behavior[J].Polymers (Basel),2020,12(9):1930.DOI: 10.3390/polym12091930.
    [35]
    Ibañez RIR,do Amaral RJFC,ReisRL,et al.3D-printed gelatin methacrylate scaffolds with controlled architecture and stiffness modulate the fibroblast phenotype towards dermal regeneration[J].Polymers (Basel),2021,13(15):2510.DOI: 10.3390/polym13152510.
    [36]
    YuanX,LiL,LiuH,et al.Strategies for improving adipose-derived stem cells for tissue regeneration[J/OL].Burns Trauma,2022,10:tkac028[2022-06-06].https://pubmed.ncbi.nlm.nih.gov/35992369/.DOI: 10.1093/burnst/tkac028.
    [37]
    MamsenFP,Munthe-FogL,KringMKM,et al.Differences of embedding adipose-derived stromal cells in natural and synthetic scaffolds for dermal and subcutaneous delivery[J].Stem Cell Res Ther,2021,12(1):68.DOI: 10.1186/s13287-020-02132-5.
    [38]
    PaganelliA,TarentiniE,BenassiL,et al.Use of confocal microscopy imaging for in vitro assessment of adipose-derived mesenchymal stromal cells seeding on acellular dermal matrices: 3D reconstruction based on collagen autofluorescence[J].Skin Res Technol,2022,28(1):133-141.DOI: 10.1111/srt.13103.
    [39]
    YangHY,FierroF,SoM,et al.Combination product of dermal matrix, human mesenchymal stem cells, and timolol promotes diabetic wound healing in mice[J].Stem Cells Transl Med,2020,9(11):1353-1364.DOI: 10.1002/sctm.19-0380.
    [40]
    张鹏多肽纳米纤维水凝胶负载富血小板血浆促进创面修复的研究苏州苏州大学2020DOI:10.27351/d.cnki.gszhu.2020.003423

    张鹏.多肽纳米纤维水凝胶负载富血小板血浆促进创面修复的研究[D].苏州:苏州大学,2020.DOI:10.27351/d.cnki.gszhu.2020.003423.

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