Research advances on the mechanism of oral mucosal stem cells in promoting wound healing

Wei Zhiru; Dong Yan; Li Guangshuai; Liu Linbo

doi:10.3760/cma.j.cn501225-20220730-00321

Volume 39 Issue 5

May 2023

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Article Navigation > CHINESE JOURNAL OF BURNS AND WOUNDS > 2023 > 39(5): 496-500

Wei ZR,Dong Y,Li GS,et al.Research advances on the mechanism of oral mucosal stem cells in promoting wound healing[J].Chin J Burns Wounds,2023,39(5):496-500.DOI: 10.3760/cma.j.cn501225-20220730-00321.

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Research advances on the mechanism of oral mucosal stem cells in promoting wound healing

doi: 10.3760/cma.j.cn501225-20220730-00321

1.
Department of Plastic Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
2.
Department of General, Visceral and Transplantation Surgery, University Hospital Heidelberg, Heidelberg 69120, Germany

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Science and Technology Development Plan Program of Henan Province of China 222102310188

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Corresponding author: Liu Linbo, Email: liulinbo@zzu.edu.cn
Received Date: 2022-07-30

Abstract

Abstract

Wound healing is a complex process that requires the participation of multiple cells and cytokines. During the process of wound healing, abnormality in any stage of the process may lead to the development of a chronic refractory wound. Research has confirmed that various stem cells can promote wound healing, but some stem cells are limited in clinical application due to difficulties in isolation, susceptibility to apoptosis, ethical and legal issues. Oral mucosal stem cells (OMSCs) can avoid the above problems. This type of stem cells has the characteristics of embryonic stem cells, immune regulatory ability, and strong homogeneity. It plays an important role in the process of scarless oral wound healing, and has become a research hotspot in promoting wound healing and reducing scar formation. This article reviews the research on the mechanism, clinical application prospects, and current problems of OMSCs in promoting wound healing.
- Wound healing,
- Cytokines,
- Oral mucosal stem cells,
- Pluripotency

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Research advances on the mechanism of oral mucosal stem cells in promoting wound healing

doi: 10.3760/cma.j.cn501225-20220730-00321

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Research advances on the mechanism of oral mucosal stem cells in promoting wound healing

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