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Volume 39 Issue 10
Oct.  2023
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Article Navigation >  CHINESE JOURNAL OF BURNS AND WOUNDS  > 2023  >  39(10): 985-988
He T,Liu W,Shen CA.Research advances on application of pancreatic stone protein in the early diagnosis of sepsis[J].Chin J Burns Wounds,2023,39(10):985-988.DOI: 10.3760/cma.j.cn501225-20221120-00498.
Citation: He T,Liu W,Shen CA.Research advances on application of pancreatic stone protein in the early diagnosis of sepsis[J].Chin J Burns Wounds,2023,39(10):985-988.DOI: 10.3760/cma.j.cn501225-20221120-00498.
shu

Research advances on application of pancreatic stone protein in the early diagnosis of sepsis

doi: 10.3760/cma.j.cn501225-20221120-00498

  • Department of Burns and Plastic Surgery, the Fourth Medical Center of PLA General Hospital, Beijing 100048, China

Funds:

General Program of National Natural Science Foundation of China 82072169, 82272279

Military Logistics Scientific Research Project Health Special Project 22BJZ35

Major Program of Military Logistics Research Plan ALB18J001

More Information
  • Corresponding author: Shen Chuan'an, Email: shenchuanan@126.com
  • Received Date: 2022-11-20
    Available Online: 2023-10-26
    Abstract
  • Sepsis is a severe life-threatening syndrome characterized by an abnormal host response to infection that can rapidly evolve into septic shock and multiple organ failure. Treatment of sepsis depends on early identification and diagnosis as well as adequate and timely anti-infection and multi-organ functional support. In recent years, pancreatic stone protein has been widely studied as a new biomarker for sepsis. Existing evidence shows that compared with the commonly used inflammatory markers in clinical practice, pancreatic stone protein has higher sensitivity and specificity in the diagnosis of sepsis. It enables the early diagnosis of sepsis and assessment of the severity of septic patients to a certain extent. This article reviews the characteristics, biological functions, diagnostic features, and clinical application of pancreatic stone protein.

     

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