Strategies for the treatment and prevention of radiation-induced skin ulcers

Xia Chengde; Yang Yang

doi:10.3760/cma.j.cn501225-20240415-00134

Volume 40 Issue 8

Aug. 2024

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Article Navigation > CHINESE JOURNAL OF BURNS AND WOUNDS > 2024 > 40(8): 719-724

Xia CD,Yang Y.Strategies for the treatment and prevention of radiation-induced skin ulcers[J].Chin J Burns Wounds,2024,40(8):719-724.DOI: 10.3760/cma.j.cn501225-20240415-00134.

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Xia CD,Yang Y.Strategies for the treatment and prevention of radiation-induced skin ulcers[J].Chin J Burns Wounds,2024,40(8):719-724.DOI: 10.3760/cma.j.cn501225-20240415-00134.

Citation:

Xia CD,Yang Y.Strategies for the treatment and prevention of radiation-induced skin ulcers[J].Chin J Burns Wounds,2024,40(8):719-724.DOI: 10.3760/cma.j.cn501225-20240415-00134.

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Strategies for the treatment and prevention of radiation-induced skin ulcers

doi: 10.3760/cma.j.cn501225-20240415-00134

Xia Chengde^,,
Yang Yang

Department of Burns, Zhengzhou First People's Hospital, Zhengzhou 450004, China

Funds:

National Clinical Key Specialty Construction Project of China 2023-70

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Corresponding author: Xia Chengde, Email: 2273451508@qq.com
Received Date: 2024-04-15

Abstract

Abstract

Radiation-induced skin ulcer is the most common adverse effect of tumor radiotherapy, and it is also a serious type of ulcer among skin injuries. Due to the varying degrees of radiation damage, the surrounding tissue of ulcers has poor self-renewal ability, which leads to delayed healing of ulcers, then followed by continuous body fluid loss, infection, and other symptoms, which can be life-threatening in severe cases. Due to the damaged blood supply or necrosis, skin ulcers are prone to relapse even after healing, which is a major challenge in clinical treatment. At present, there is still a lack of specific drugs and precise administration guidelines for the treatment of radiation-induced skin ulcers, and symptomatic treatment is the main treatment in clinical practice. Based on the clinical practical experience of authors' team and current relevant literature, this paper proposed corresponding drug therapy, hyperbaric oxygen assisted therapy, surgery therapy, and early prevention strategies for radiation-induced skin ulcers at different stages, in order to provide reference for clinical treatment and prevention of radiation-induced skin ulcer.
- Skin ulcer,
- Chemistry, pharmaceutical,
- Hyperbaric oxygenation,
- Surgical procedures, operative,
- Radiation injuries,
- Wound repair

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References

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Strategies for the treatment and prevention of radiation-induced skin ulcers

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