Multidisciplinary expert consensus on tophus damage grading and surgical treatment (2025 edition)

doi:10.3760/cma.j.cn501225-20240721-00274

Jan. 2026

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Article Navigation > CHINESE JOURNAL OF BURNS AND WOUNDS > 2026 > 42(1): 7-18

Wound Repair Professional Committee of Chinese Medical Doctor Association.Multidisciplinary expert consensus on tophus damage grading and surgical treatment (2025 edition)[J].Chin J Burns Wounds,2026,42(1):7-18.DOI: 10.3760/cma.j.cn501225-20240721-00274.

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Multidisciplinary expert consensus on tophus damage grading and surgical treatment (2025 edition)

doi: 10.3760/cma.j.cn501225-20240721-00274

Funds:

Hainan Academician Innovative Platform Project YSPTZX202028

Received Date: 2024-07-21

Abstract

Abstract

Tophi, a severe complication of advanced gout, develop in approximately 12% to 53% of patients with gout. The treatment of bone and joint damages and chronic refractory wounds caused by tophi presents considerable clinical challenges. Currently, there is no unified standard for the optimal surgical timing, perioperative management, and treatment approaches for this condition. To address this, the Wound Repair Professional Committee of Chinese Medical Doctor Association convened a multidisciplinary panel of senior experts in wound repair, plastic surgery, orthopedics & joint surgery, rheumatology and immunology, radiology, and nursing and wound management. Based on the literature evidence combined with expert opinion, the panel employed nominal group and Delphi methods, and a grading standard (levels 1 to 4) defining the extent of tophi damage and the treatment principle were established for the first time to ensure homogeneity of surgical treatment; 14 recommendations on the diagnosis and treatment of tophi were proposed, providing practical guidance for the surgical treatment of tophi.
- Gout,
- Diagnosis,
- Therapy,
- Tophi,
- Consensus,
- Damage degree grading

Pan Yunchuan, the Plastic and Cosmetic Center, Hainan Fifth People's Hospital, Haikou 570311, China, Email: pychuan@qq.comFu Xiaobing, Key Laboratory for Wound Repair and Regeneration, Medical Innovation Research Department, the PLA General Hospital, Beijing 100853, China, Email: fuxiaobing@vip.sina.comHuang Yuesheng, Institute of Wound Repair and Regenerative Medicine, Southern University of Science and Technology School of Medicine, Shenzhen 518055, China, Email: huangys@sustech.edu.cn

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References(96)

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Multidisciplinary expert consensus on tophus damage grading and surgical treatment (2025 edition)

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Multidisciplinary expert consensus on tophus damage grading and surgical treatment (2025 edition)

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