Email Alerts
RSS
Volume 42 Issue 7
Jul.  2026
Turn off MathJax
Article Contents
Article Navigation >  CHINESE JOURNAL OF BURNS AND WOUNDS  > 2026  >  42(7): 694-699
Sun LL,Ding L,Zhang LC,et al.Interpretation of the 2025 American Burn Association Clinical Practice Guideline on blood product transfusion in burn care[J].Chin J Burns Wounds,2026,42(7):694-699.DOI: 10.3760/cma.j.cn501225-20251210-00516.
Citation: Sun LL,Ding L,Zhang LC,et al.Interpretation of the 2025 American Burn Association Clinical Practice Guideline on blood product transfusion in burn care[J].Chin J Burns Wounds,2026,42(7):694-699.DOI: 10.3760/cma.j.cn501225-20251210-00516.
shu

Interpretation of the 2025 American Burn Association Clinical Practice Guideline on blood product transfusion in burn care

doi: 10.3760/cma.j.cn501225-20251210-00516

  • Department of Burns, the Second Affiliated Hospital of Kunming Medical University, Kunming 650101, China

Funds:

Yunnan Revitalization Talent Support Planning Program RSC2019MY018

Scientific Research Fund Project of Education Department of Yunnan Province 2024J0322

More Information
  • Corresponding author: Liu Wenjun, Email: 86550558@qq.com
  • Received Date: 2025-12-10
    Available Online: 2026-07-23
    Abstract
  • The American Burn Association Clinical Practice Guideline on blood product transfusion in burn care was released in July 2025. Based on the PICO (Population, Intervention, Comparison, Outcome) framework and available evidence, the guideline provided evidence-based recommendations for blood product transfusion issues during hospitalization of adult burn patients, covering the management of transfusion indications, viscoelastic testing, the use of erythropoietin and tranexamic acid, and blood product transfusion strategies, etc. This article interpreted the key points of the guideline to facilitate their understanding and application by clinical medical professionals.

     

    • FullText(HTML)
  • loading
    • References(52)
  • [1]
    段德庆多中心大面积烧伤患者的输血情况回顾及其相关因素分析南昌南昌大学2023DOI:10.27232/d.cnki.gnchu.2023.000576

    段德庆.多中心大面积烧伤患者的输血情况回顾及其相关因素分析[D].南昌:南昌大学,2023.DOI:10.27232/d.cnki.gnchu.2023.000576.
    [2]
    SuK, XueFS, XueZJ, et al. Clinical characteristics and risk factors of early acute kidney injury in severely burned patients[J]. Burns, 2021,47(2):498-499. DOI: 10.1016/j.burns.2020.08.018.
    [3]
    张寅, 马珍珠, 吴蓓雯, 等. 特重度烧伤患者血流感染风险早期预测模型的建立及其预测价值分析[J].中华烧伤杂志,2021,37(6):530-537. DOI: 10.3760/cma.j.cn501120-20210114-00021.
    [4]
    WallaceD, LavrentievaA, RomanowskiKS, et al. American Burn Association Clinical Practice Guideline on blood product transfusion in burn care[J]. J Burn Care Res, 2025,46(6):1155-1170. DOI: 10.1093/jbcr/iraf021.
    [5]
    TichilI, RosenblumS, PaulE, et al. Treatment of anaemia in patients with acute burn injury: a study of blood transfusion practices[J]. J Clin Med, 2021,10(3):476.DOI: 10.3390/jcm10030476.
    [6]
    王默然, 王峻, 葛艳玲. 烧伤患者住院期间用血情况影响因素的回顾性分析[J].中国输血杂志,2021,34(2):143-146. DOI: 10.13303/j.cjbt.issn.1004-549x.2021.02.012.
    [7]
    KasererA, RösslerJ, SlankamenacK, et al. Impact of allogeneic blood transfusions on clinical outcomes in severely burned patients[J]. Burns, 2020,46(5):1083-1090. DOI: 10.1016/j.burns.2019.11.005.
    [8]
    孙林利, 刘丽红, 向路艳, 等. 2023版美国烧伤协会《烧伤休克复苏临床实践指南》解读[J].中华烧伤与创面修复杂志,2024,40(10):996-1000. DOI: 10.3760/cma.j.cn501225-20240218-00061.
    [9]
    RegliIB, StrapazzonG, FallaM, et al. Long-term sequelae of frostbite-a scoping review[J]. Int J Environ Res Public Health, 2021,18(18): 9655.DOI: 10.3390/ijerph18189655.
    [10]
    段德庆, 陈永, 邓鸿敖, 等. 大面积烧伤患者输血情况的多中心回顾及影响因素分析[J].中华烧伤与创面修复杂志,2023,39(11):1047-1056. DOI: 10.3760/cma.j.cn501225-20230417-00128.
    [11]
    周吉华, 陆国平. 儿童成分输血与输全血的选择[J].中国实用儿科杂志,2020,35(12):953-958. DOI: 10.19538/j.ek2020120608.
    [12]
    黄小娟, 辛艳泓. 810例烧伤患者的成分输血分析[J].西北国防医学杂志,2018,39(2):111-114. DOI: 10.16021/j.cnki.1007-8622.2018.02.011.
    [13]
    KilyewalaC, AlenyoR, SsentongoR. Determinants and time to blood transfusion among thermal burn patients admitted to Mulago Hospital[J]. BMC Res Notes, 2017,10(1):258. DOI: 10.1186/s13104-017-2580-2.
    [14]
    HébertPC, WellsG, BlajchmanMA, et al. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group[J]. N Engl J Med, 1999, 340(6): 409-417.DOI: 10.1056/NEJM199902113400601.
    [15]
    PalmieriTL, HolmesJH, ArnoldoB, et al. Transfusion requirement in burn care evaluation (TRIBE): a multicenter randomized prospective trial of blood transfusion in major burn injury[J]. Ann Surg, 2017,266(4):595-602. DOI: 10.1097/SLA.0000000000002408.
    [16]
    CozYataco AO, SoghierI, HébertPC, et al. Red blood cell transfusion in critically ill adults: an American College of Chest Physicians clinical practice guideline[J]. Chest, 2025,167(2):477-489. DOI: 10.1016/j.chest.2024.09.016.
    [17]
    TacconeFS, RynkowskiCB, MøllerK, et al. Restrictive vs liberal transfusion strategy in patients with acute brain injury: the TRAIN randomized clinical trial[J]. JAMA, 2024,332(19):1623-1633. DOI: 10.1001/jama.2024.20424.
    [18]
    LiverTox: clinical and research information on drug-induced liver injury [DB/OL]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases, 2012(2017-12-05)[2025-12-10].https://pubmed.ncbi.nlm.nih.gov/31643176/. https://pubmed.ncbi.nlm.nih.gov/31643176/
    [19]
    StillJM, BelcherK, LawEJ, et al. A double-blinded prospective evaluation of recombinant human erythropoietin in acutely burned patients[J]. J Trauma, 1995,38(2):233-236. DOI: 10.1097/00005373-199502000-00015.
    [20]
    MattichJ, KruppS, ChioleroR, et al. Erythropoietin therapy in burns: a pilot study[J]. Eur J Plast Surg, 1993,16:298-302.
    [21]
    周烁, 罗振中, 徐国海, 等. 重组人促红细胞生成素用于围术期纠正贫血的研究进展[J]. 临床麻醉学杂志,2016,32(7):709-712.
    [22]
    马庆宏, 张润, 严旭东, 等. 促红细胞生成素联合氨甲环酸改善股骨粗隆间骨折围手术期贫血及失血的疗效与安全性分析[J].南京医科大学学报(自然科学版),2024,44(6):826-831. DOI: 7655/NYDXBNSN240063.
    [23]
    阮如昕, 郑欣, 白超文, 等. 重组人促红细胞生成素用于全髋关节置换术的评价[J].中国矫形外科杂志,2020,28(17):1537-1542. DOI: 10.3977/j.issn.1005-8478.2020.17.01.
    [24]
    陈永杰重组人促红素(rhEPO)治疗腰椎融合术患者围术期贫血的有效性和安全性武汉华中科技大学2022DOI:10.27157/d.cnki.ghzku.2022.006004

    陈永杰. 重组人促红素(rhEPO)治疗腰椎融合术患者围术期贫血的有效性和安全性[D]. 武汉:华中科技大学, 2022. DOI:10.27157/d.cnki.ghzku.2022.006004.
    [25]
    王文丽, 姚依婷, 杨春. 氨甲环酸围术期应用进展[J].中国临床药理学与治疗学,2024,29(2):198-206.
    [26]
    孙晶, 孟昌, 赵月, 等. 氨甲环酸在烧伤患者围术期应用安全性和有效性的Meta分析[J].中国临床药理学杂志,2025,41(18):2667-2673. DOI: 10.13699/j.cnki.1001-6821.2025.18.017.
    [27]
    BhatiaN, SenI, KumariK, et al. Impact of single dose intravenous tranexamic acid on peri-operative blood transfusion requirements in burn patients: a prospective, randomized trial[J]. Egypt J Anaesth,2017,33(3):251-255. DOI: 10.1016/j.egja.2017.05.004.
    [28]
    KumarSA, KumarP, SubairM, et al. Effect of single dose intravenous tranexamic acid on blood loss in tangential excision of burn wounds-a double blind randomised controlled trial[J]. Burns, 2022,48(6):1311-1318. DOI: 10.1016/j.burns.2021.08.021.
    [29]
    秦冠伦, 丁玉美. 血栓弹力图和旋转血栓弹力图在创伤患者围术期的应用进展[J].中国医疗设备,2024,39(3):174-180. DOI: 10.3969/j.issn.1674-1633.2024.03.029.
    [30]
    赵婧楠, 蒋航, 陈宾, 等. 重症烧伤患者早期凝血功能变化探究[J]. 中华烧伤与创面修复杂志,2023,39(11):1057-1063. DOI: 10.3760/cma.j.cn501120-20210915-00320.
    [31]
    樊凤艳, 马越云. 用PT/APTT指导血浆输注的几种特殊情况[J]. 临床输血与检验,2024,26(1):23-28. DOI: 10.3969/j.issn.1671-2587.2024.01.004.
    [32]
    SchadenE, KimbergerO, KraincukP, et al. Perioperative treatment algorithm for bleeding burn patients reduces allogeneic blood product requirements[J]. Br J Anaesth, 2012,109(3):376-381. DOI: 10.1093/bja/aes186.
    [33]
    RossaintR, AfshariA, BouillonB, et al. The European guideline on management of major bleeding and coagulopathy following trauma: sixth edition[J]. Crit Care, 2023,27(1):80. DOI: 10.1186/s13054-023-04327-7.
    [34]
    CochraneC, ChinnaS, UmJY, et al. Site-of-care viscoelastic assay in major trauma improves outcomes and is cost neutral compared with standard coagulation tests[J]. Diagnostics (Basel),2020,10(7):486. DOI: 10.3390/diagnostics10070486.
    [35]
    LammersDT, MarencoCW, MorteKR, et al. Viscoelastic testing in combat resuscitation: is it time for a new standard?[J]. J Trauma Acute Care Surg, 2020,89(1):145-152. DOI: 10.1097/TA.0000000000002634.
    [36]
    CrochemoreT, GörlingerK, LanceMD. Early goal-directed hemostatic therapy for severe acute bleeding management in the intensive care unit: a narrative review[J]. Anesth Analg, 2024,138(3):499-513. DOI: 10.1213/ANE.0000000000006756.
    [37]
    SantosAS, OliveiraA, BarbosaM, et al. Viscoelastic haemostatic assays in the perioperative period of surgical procedures: systematic review and meta-analysis[J]. J Clin Anesth, 2020,64:109809. DOI: 10.1016/j.jclinane.2020.109809.
    [38]
    KoamiH, SakamotoY, MatsuokaA, et al. Thromboelastometric analysis of the correlation between burn-induced coagulopathy and severity of burn injury[J]. Cureus, 2024,16(2):e54489. DOI: 10.7759/cureus.54489.
    [39]
    SahliSD, PedrazziN, BraunJ, et al. Effect of a factor-based coagulation management on blood product use after major burn injury: a retrospective cohort study[J]. Burns, 2021,47(7):1486-1494. DOI: 10.1016/j.burns.2021.08.015.
    [40]
    BrillJB, BrennerM, DuchesneJ, et al. The role of TEG and ROTEM in damage control resuscitation[J]. Shock, 2021,56(1S):52-61. DOI: 10.1097/SHK.0000000000001686.
    [41]
    冶春娟, 张春, 李嘉璐, 等. 原发性肝癌患者血栓弹力图的临床特征及其对凝血功能的评估价值[J].临床肝胆病杂志,2026,42(1):111-116. DOI: 10.12449/JCH260113.
    [42]
    BuellTJ, TaylorDG, ChenCJ, et al. Rotational thromboelastometry-guided transfusion during lumbar pedicle subtraction osteotomy for adult spinal deformity: preliminary findings from a matched cohort study[J]. Neurosurg Focus, 2019,46(4):E17. DOI: 10.3171/2019.1.FOCUS18572.
    [43]
    苏莉,李晓庆,仲青,等.血栓弹力图检测在产妇术后大出血输血治疗中的应用及对凝血功能的影响[J].中国妇产科临床杂志,2025,26(5):449-451.DOI: 10.13390/j.issn.1672-1861.2025.05.018.
    [44]
    HousingerTA, LangD, WardenGD. A prospective study of blood loss with excisional therapy in pediatric burn patients[J]. J Trauma, 1993,34(2):262-263. DOI: 10.1097/00005373-199302000-00015.
    [45]
    SperryJL, OchoaJB, GunnSR, et al. An FFP:PRBC transfusion ratio ≥1:1.5 is associated with a lower risk of mortality after massive transfusion[J]. J Trauma, 2008,65(5):986-993. DOI: 10.1097/TA.0b013e3181878028.
    [46]
    GalganskiLA, GreenhalghDG, SenS, et al. Randomized comparison of packed red blood cell-to-fresh frozen plasma transfusion ratio of 4: 1 vs 1: 1 during acute massive burn excision[J]. J Burn Care Res, 2017,38(3):194-201. DOI: 10.1097/BCR.0000000000000468.
    [47]
    HolcombJB, WadeCE, MichalekJE, et al. Increased plasma and platelet to red blood cell ratios improves outcome in 466 massively transfused civilian trauma patients[J]. Ann Surg, 2008,248(3):447-458. DOI: 10.1097/SLA.0b013e318185a9ad.
    [48]
    ConsunjiR, ElseedA, El-MenyarA, et al. The effect of massive transfusion protocol implementation on the survival of trauma patients: a systematic review and meta-analysis[J]. Blood Transfus, 2020, 18(6): 434-445. DOI: 10.2450/2020.0065-20.
    [49]
    王雪欣严重烧伤患者围手术期成分输血情况和影响因素分析天津天津医科大学2018

    王雪欣. 严重烧伤患者围手术期成分输血情况和影响因素分析[D].天津:天津医科大学, 2018.
    [50]
    秦婷婷, 刘广锋, 孙小红, 等. 不同成分输血比例对创伤大出血患者血栓弹力图检测结果的影响及预后分析[J]. 临床血液学杂志, 2024, 37(12): 864-868. DOI: 10.13201/j.issn.1004-2806.2024.12.005.
    [51]
    林先娘, 赖寒光, 杨晓明. 成分输血比例对创伤患者输血安全性及其凝血功能的影响[J]. 中国卫生标准管理, 2025, 16(16): 163-166. DOI: 10.3969/j.issn.1674-9316.2025.16.037.
    [52]
    商哲, 王焕成, 张茜, 等. 不同比例成分输血在创伤大出血患者中的应用效果比较[J]. 临床医学, 2024, 44(11): 66-68. DOI: 10.19528/j.issn.1003-3548.2024.11.020.
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索
    Get Citation
    PDF
    XML

    Article Metrics

    Article views (77) PDF downloads(9) Cited by()
    Proportional views
    Related

    Copyright © Chinese Journal of Burns京ICP备07035254号-14

    E-mail：shaoshangzazhi@163.com

    Website：https://zhsszz.xml-journal.net/

    Supported by: Beijing Renhe Information Technology Co. Ltd    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return