Advances in the mechanism of mesenchymal stem cells in promoting wound healing

Zhu Wenjing; Sun Haobo; Lyu Guozhong

doi:10.3760/cma.j.issn.1009-2587.2015.06.026

Volume 31 Issue 6

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Article Navigation > CHINESE JOURNAL OF BURNS AND WOUNDS > 2015 > 31(6): 476-478

Zhu Wenjing, Sun Haobo, Lyu Guozhong. Advances in the mechanism of mesenchymal stem cells in promoting wound healing[J]. Chin j Burns, 2015, 31(6): 476-478. Doi: 10.3760/cma.j.issn.1009-2587.2015.06.026

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Advances in the mechanism of mesenchymal stem cells in promoting wound healing

doi: 10.3760/cma.j.issn.1009-2587.2015.06.026

Department of Burns and Plastic Surgery, the Third People's Hospital of Wuxi City, Wuxi 214041, China

Received Date: 2015-04-14
Available Online: 2021-10-28
Publish Date: 2015-12-20

Abstract

Abstract

Mesenchymal stem cells possess the ability of self-renewal and multiple differentiation potential, thus exert immunomodulatory effect during tissue repair. Mesenchymal stem cells can stimulate angiogenesis and promote tissue repair through transdifferentiation and secreting a variety of growth factors and cytokines. This review outlines the advances in the mechanism of mesenchymal stem cells in promoting wound healing, including alleviation of inflammatory response, induction of angiogenesis, and promotion of migration of mesenchymal stem cells to the site of tissue injury.
- Mesenchymal stem cells,
- Wound healing,
- Inflammation,
- Angiogenesis