Re-understanding the physiological and pathophysiological roles of neutrophils

Sun Bingwei; Huang Jiamin

doi:10.3760/cma.j.cn501120-20211122-00391

Volume 38 Issue 2

Feb. 2022

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Article Navigation > CHINESE JOURNAL OF BURNS AND WOUNDS > 2022 > 38(2): 109-113

Sun BW,Huang JM.Re-understanding the physiological and pathophysiological roles of neutrophils[J].Chin J Burns Wounds,2022,38(2):109-113.DOI: 10.3760/cma.j.cn501120-20211122-00391.

Citation:

Sun BW,Huang JM.Re-understanding the physiological and pathophysiological roles of neutrophils[J].Chin J Burns Wounds,2022,38(2):109-113.DOI: 10.3760/cma.j.cn501120-20211122-00391.

Citation:

Sun BW,Huang JM.Re-understanding the physiological and pathophysiological roles of neutrophils[J].Chin J Burns Wounds,2022,38(2):109-113.DOI: 10.3760/cma.j.cn501120-20211122-00391.

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Re-understanding the physiological and pathophysiological roles of neutrophils

doi: 10.3760/cma.j.cn501120-20211122-00391

Sun Bingwei^,,
Huang Jiamin

Department of Burns and Plastic Surgery, Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou 215002, China

Funds:

Major Program of National Natural Science Foundation of China U21A20370

General Program of National Natural Science Foundation of China 82072217, 81772135

Special Program of Basic Research Plan (Natural Science Foundation) of Jiangsu Province of China BK20201178

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Corresponding author: Sun Bingwei, Email: sunbinwe@hotmail.com
Received Date: 2021-11-22

Abstract

Abstract

Neutrophils have always been considered as a short-lived and homogeneous cell type in the innate immune system, which have limited pro-inflammatory or anti-inflammatory effects. However, in recent 10 years, the understanding of neutrophils has been undergoing some kind of revival as researches progressed. The researches on the heterogeneity of neutrophils and the mechanism of their interaction with other immune cells have promoted the researchers to re-understand the physiological and pathophysiological roles of neutrophils. In the following decades, with the development of single-cell sequencing technology, spatial transcriptome sequencing technology, and multi-omics combined sequencing technology, researchers will have a better understanding of the biological behaviors of neutrophils. This paper briefly reviews the biological behaviors of neutrophils and their roles in various diseases in recent years.
- Cell death,
- Chemotaxis,
- Hetero- geneity,
- Neutrophils

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References

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Re-understanding the physiological and pathophysiological roles of neutrophils

doi: 10.3760/cma.j.cn501120-20211122-00391

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Re-understanding the physiological and pathophysiological roles of neutrophils

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