Research advances on the role and mechanism of chitosan-based wound dressing in wound healing

Hu Zonghao; Ayixiemu·Yu sufu; Qu Yue; Xie Jinhong; Yin Lihua

doi:10.3760/cma.j.cn501225-20220506-00172

Volume 39 Issue 4

Apr. 2023

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Article Navigation > CHINESE JOURNAL OF BURNS AND WOUNDS > 2023 > 39(4): 386-390

Wu MY,He PY,Duan Y,et al.Effects of stimulator of interferon gene on ferroptosis mediated by acyl-CoA synthetase long-chain family member 4 in mouse dendritic cells under sepsis[J].Chin J Burns Wounds,2024,40(10):920-929.DOI: 10.3760/cma.j.cn501225-20240518-00184.

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Hu ZH,Ayixiemu·Y,Qu Y,et al.Research advances on the role and mechanism of chitosan-based wound dressing in wound healing[J].Chin J Burns Wounds,2023,39(4):386-390.DOI: 10.3760/cma.j.cn501225-20220506-00172.

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Research advances on the role and mechanism of chitosan-based wound dressing in wound healing

doi: 10.3760/cma.j.cn501225-20220506-00172

Department of Oral Implant, School/Hospital of Stomatology, Lanzhou University, Lanzhou 730000, China

Funds:

Gansu Provincial Science and Technology Plan International Cooperation Special Project 18YF1WA116

Gansu Provincial Special Fund for Guiding Scientific and Technological Innovation and Development Competitive Project 2018ZX-10

Lanzhou Talent Innovation and Entrepreneurship Project 2017-RC-31

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Corresponding author: Yin Lihua, Email: yinlh@lzu.edu.cn
Received Date: 2022-05-06

Abstract

Abstract

The skin is the first barrier to maintain the stability of internal environment of the body and resist harmful factors of external environment, and is easily damaged because of various external factors. When full-thickness skin defects reach a certain level, it is difficult for the skin to repair itself, so wound dressings are needed to promote wound healing. Seeking an ideal dressing that can promote wound healing has long been a hot research topic. Chitosan is a unique biopolysaccharide polymer with good biocompatibility, biodegradability, antibacterial activity, and thermal stability, which has great potential in the development and application of wound dressings. Based on the introduction of properties of chitosan, this article reviews the role and mechanism of chitosan-based wound dressings in wound healing, and summarizes the hemostatic effect, antibacterial effect, delivery effect, and tissue regeneration promotion effect of chitosan, aiming to provide a certain reference for the research and development of new chitosan-based wound dressings in the future.
- Chitosan,
- Biological dressings,
- Tissue engineering,
- Wound healing,
- Mechanism of action

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References

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Research advances on the role and mechanism of chitosan-based wound dressing in wound healing

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Research advances on the role and mechanism of chitosan-based wound dressing in wound healing

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