Research advance on the effects of surface interface topographies and physicochemical properties of biomaterial on macrophages and their application in wound healing

Zhang Wei; Shao Jiaming; Yang Min; Liu Huan; Han Chunmao; Wang Xingang

doi:10.3760/cma.j.cn501225-20231110-00190

Volume 40 Issue 9

Sep. 2024

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Article Navigation > CHINESE JOURNAL OF BURNS AND WOUNDS > 2024 > 40(9): 891-896

Zhang W,Shao JM,Yang M,et al.Research advance on the effects of surface interface topographies and physicochemical properties of biomaterial on macrophages and their application in wound healing[J].Chin J Burns Wounds,2024,40(9):891-896.DOI: 10.3760/cma.j.cn501225-20231110-00190.

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Research advance on the effects of surface interface topographies and physicochemical properties of biomaterial on macrophages and their application in wound healing

doi: 10.3760/cma.j.cn501225-20231110-00190

1.
Department of Plastic Surgery, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China
2.
Department of Burn and Wound Repair, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China
3.
Department of Wound Repair, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China

Funds:

National Key Research and Development Program of China 2022YFC2403100

General Program of National Natural Science Foundation of China 82172198

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Corresponding author: Wang Xingang, Email: wangxingang8157@zju.edu.cn
Received Date: 2023-11-10
Available Online: 2024-09-27

Abstract

Abstract

The human immune system plays a key role in maintaining tissue homeostasis and disease progression. The development of biomaterials that can regulate the innate immune system and adapt to the immune system has great application prospects in the field of tissue engineering. This paper discusses how to design the surface interface topographies or the physicochemical properties of biomaterials, to regulate the fate of macrophages, such as activation, polarization, adhesion, migration, proliferation, and secretion. At the same time, the application of these biomaterials with immunoregulation function in the field of wound healing is discussed. In addition, this paper also put forward the limitations of biomaterials in immunoregulation applications and prospected the future development directions.
- Macrophages,
- Biocompatible materials,
- Immunity,
- Polarization,
- Surface interface topographies,
- Wound repair

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[1]	ShalabiMM, GortemakerA, Van'tHof MA, et al. Implant surface roughness and bone healing: a systematic review[J]. J Dent Res, 2006,85(6):496-500. DOI: 10.1177/154405910608500603.
[2]	BarthKA, WaterfieldJD, BrunetteDM. The effect of surface roughness on RAW 264.7 macrophage phenotype[J]. J Biomed Mater Res A, 2013,101(9):2679-2688. DOI: 10.1002/jbm.a.34562.
[3]	ZhangY, ChengX, JansenJA, et al. Titanium surfaces characteristics modulate macrophage polarization[J]. Mater Sci Eng C Mater Biol Appl, 2019,95:143-151. DOI: 10.1016/j.msec.2018.10.065.
[4]	AbariciaJO, ShahAH, ChaubalM, et al. Wnt signaling modulates macrophage polarization and is regulated by biomaterial surface properties[J]. Biomaterials, 2020,243:119920. DOI: 10.1016/j.biomaterials.2020.119920.
[5]	AveryD, MorandiniL, SheakleyLS, et al. Canonical Wnt signaling enhances pro-inflammatory response to titanium by macrophages[J]. Biomaterials, 2022,289:121797. DOI: 10.1016/j.biomaterials.2022.121797.
[6]	HotchkissKM, ReddyGB, HyzySL, et al. Titanium surface characteristics, including topography and wettability, alter macrophage activation[J]. Acta Biomater, 2016,31:425-434. DOI: 10.1016/j.actbio.2015.12.003.
[7]	HamletSM, LeeR, MoonHJ, et al. Hydrophilic titanium surface-induced macrophage modulation promotes pro-osteogenic signalling[J]. Clin Oral Implants Res, 2019,30(11):1085-1096. DOI: 10.1111/clr.13522.
[8]	MironRJ, BohnerM, ZhangY, et al. Osteoinduction and osteoimmunology: emerging concepts[J]. Periodontol 2000, 2024,94(1):9-26. DOI: 10.1111/prd.12519.
[9]	ChenY, LuoZ, MengW, et al. Decoding the "fingerprint" of implant materials: insights into the foreign body reaction[J]. Small, 2024,20(23):e2310325. DOI: 10.1002/smll.202310325.
[10]	BarkalAA, WeiskopfK, KaoKS, et al. Engagement of MHC class Ⅰ by the inhibitory receptor LILRB1 suppresses macrophages and is a target of cancer immunotherapy[J]. Nat Immunol, 2018,19(1):76-84. DOI: 10.1038/s41590-017-0004-z.
[11]	JiL, ZhaoX, ZhangB, et al. Slc6a8-mediated creatine uptake and accumulation reprogram macrophage polarization via regulating cytokine responses[J]. Immunity, 2019,51(2):272-284.e7. DOI: 10.1016/j.immuni.2019.06.007.
[12]	LiJ, JiangX, LiH, et al. Tailoring materials for modulation of macrophage fate[J]. Adv Mater, 2021,33(12):e2004172. DOI: 10.1002/adma.202004172.
[13]	SunL, ChenX, MaK, et al. Novel titanium implant: a 3D multifunction architecture with charge-trapping and piezoelectric self-stimulation[J]. Adv Healthc Mater, 2023,12(11):e2202620. DOI: 10.1002/adhm.202202620.
[14]	DengH, YangX, WangH, et al. Tailoring the surface charges of iron-crosslinked dextran nanogels towards improved tumor-associated macrophage targeting[J]. Carbohydr Polym, 2024,325:121585. DOI: 10.1016/j.carbpol.2023.121585.
[15]	XiaoB, LiuY, ChandrasiriI, et al. Impact of nanoparticle physicochemical properties on protein corona and macrophage polarization[J/OL]. ACS Appl Mater Interfaces, 2023(2023-04-14)[2023-11-10].https://pubmed.ncbi.nlm.nih.gov/36916683/.DOI: 10.1021/acsami.2c22471.[published online ahead of print].
[16]	GargK, PullenNA, OskeritzianCA, et al. Macrophage functional polarization (M1/M2) in response to varying fiber and pore dimensions of electrospun scaffolds[J]. Biomaterials, 2013,34(18):4439-4451. DOI: 10.1016/j.biomaterials.2013.02.065.
[17]	HoriiT, TsujimotoH, HagiwaraA, et al. Effects of fiber diameter and spacing size of an artificial scaffold on the in vivo cellular response and tissue remodeling[J]. ACS Appl Bio Mater, 2021,4(9):6924-6936. DOI: 10.1021/acsabm.1c00572.
[18]	MoonH, CremmelCV, KulpaA, et al. Novel grooved substrata stimulate macrophage fusion, CCL2 and MMP-9 secretion[J]. J Biomed Mater Res A, 2016, 104(9):2243-2254. DOI: 10.1002/jbm.a.35757.
[19]	WangT, LuuTU, ChenA, et al. Topographical modulation of macrophage phenotype by shrink-film multi-scale wrinkles[J]. Biomater Sci, 2016,4(6):948-952. DOI: 10.1039/c6bm00224b.
[20]	BartneckM, HeffelsKH, PanY, et al. Inducing healing-like human primary macrophage phenotypes by 3D hydrogel coated nanofibres[J]. Biomaterials, 2012,33(16):4136-4146. DOI: 10.1016/j.biomaterials.2012.02.050.
[21]	ZhuG, ZhangR, XieQ, et al. Shish-kebab structure fiber with nano and micro diameter regulate macrophage polarization for anti-inflammatory and bone differentiation[J]. Mater Today Bio, 2023,23:100880. DOI: 10.1016/j.mtbio.2023.100880.
[22]	WuS, ShanZ, XieL, et al. Mesopore controls the responses of blood clot-immune complex via modulating fibrin network[J]. Adv Sci (Weinh), 2022,9(3):e2103608. DOI: 10.1002/advs.202103608.
[23]	MaharaA, KojimaK, YamamotoM, et al. Accelerated tissue regeneration in decellularized vascular grafts with a patterned pore structure[J]. J Mater Chem B, 2022,10(14):2544-2550. DOI: 10.1039/d1tb02271g.
[24]	McWhorterFY, WangT, NguyenP, et al. Modulation of macrophage phenotype by cell shape[J]. Proc Natl Acad Sci U S A, 2013,110(43):17253-17258. DOI: 10.1073/pnas.1308887110.
[25]	BartneckM, SchulteVA, PaulNE, et al. Induction of specific macrophage subtypes by defined micro-patterned structures[J]. Acta Biomater, 2010,6(10):3864-3872. DOI: 10.1016/j.actbio.2010.04.025.
[26]	MohiuddinM, PanHA, HungYC, et al. Control of growth and inflammatory response of macrophages and foam cells with nanotopography[J]. Nanoscale Res Lett, 2012,7(1):394. DOI: 10.1186/1556-276X-7-394.
[27]	VeisehO, DoloffJC, MaM, et al. Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates[J]. Nat Mater, 2015,14(6):643-651. DOI: 10.1038/nmat4290.
[28]	RakicM, RadunovicM, Petkovic-CurcinA, et al. Study on the immunopathological effect of titanium particles in peri-implantitis granulation tissue: a case-control study[J]. Clin Oral Implants Res,2022, 33(6):656-666. DOI: 10.1111/clr.13928.
[29]	Toledano-SerrabonaJ, Camps-FontO, de MoraesDP, et al. Ion release and local effects of titanium metal particles from dental implants: an experimental study in rats[J]. J Periodontol, 2023,94(1):119-129. DOI: 10.1002/JPER.22-0091.
[30]	TylekT, BlumC, HrynevichA, et al. Precisely defined fiber scaffolds with 40 μm porosity induce elongation driven M2-like polarization of human macrophages[J]. Biofabrication, 2020,12(2):025007. DOI: 10.1088/1758-5090/ab5f4e.
[31]	SommerfeldSD, CherryC, SchwabRM, et al. Interleukin-36γ-producing macrophages drive IL-17-mediated fibrosis[J]. Sci Immunol, 2019,4(40):eaax4783.DOI: 10.1126/sciimmunol.aax4783.
[32]	HeC , YuL , YaoH ,et al. Combinatorial photothermal 3D‐printing scaffold and checkpoint blockade inhibits growth/metastasis of breast cancer to bone and accelerates osteogenesis[J].Adv Funct Mater, 2021, 31:2006214. DOI: 10.1002/adfm.202006214.
[33]	LiuH, WuQ, LiuS, et al. The role of integrin αvβ3 in biphasic calcium phosphate ceramics mediated M2 Macrophage polarization and the resultant osteoinduction[J]. Biomaterials, 2024,304:122406. DOI: 10.1016/j.biomaterials.2023.122406.
[34]	ZhouK, YangC, ShiK, et al. Activated macrophage membrane-coated nanoparticles relieve osteoarthritis-induced synovitis and joint damage[J]. Biomaterials, 2023,295:122036. DOI: 10.1016/j.biomaterials.2023.122036.
[35]	LiJ, LiL, WuT, et al. An injectable thermosensitive hydrogel containing resveratrol and dexamethasone-loaded carbonated hydroxyapatite microspheres for the regeneration of osteoporotic bone defects[J]. Small Methods, 2024,8(1):e2300843. DOI: 10.1002/smtd.202300843.
[36]	WhitakerR, Hernaez-EstradaB, HernandezRM, et al. Immunomodulatory biomaterials for tissue repair[J]. Chem Rev, 2021,121(18):11305-11335. DOI: 10.1021/acs.chemrev.0c00895.
[37]	GroseR, WernerS. Wound-healing studies in transgenic and knockout mice[J]. Mol Biotechnol, 2004,28(2):147-166. DOI: 10.1385/MB:28:2:147.
[38]	Al SadounH. Macrophage phenotypes in normal and diabetic wound healing and therapeutic interventions[J]. Cells, 2022, 11(15):2430. DOI: 10.3390/cells11152430.
[39]	VelnarT, BaileyT, SmrkoljV. The wound healing process: an overview of the cellular and molecular mechanisms[J]. J Int Med Res, 2009,37(5):1528-1542. DOI: 10.1177/147323000903700531.
[40]	MartinezFO, SicaA, MantovaniA, et al. Macrophage activation and polarization[J]. Front Biosci, 2008,13:453-461. DOI: 10.2741/2692.
[41]	ElliottMR, KosterKM, MurphyPS. Efferocytosis signaling in the regulation of macrophage inflammatory responses[J]. J Immunol, 2017,198(4):1387-1394. DOI: 10.4049/jimmunol.1601520.
[42]	WangH, HuangR, BaiL, et al. Extracellular matrix-mimetic immunomodulatory hydrogel for accelerating wound healing[J]. Adv Healthc Mater, 2023,12(27):e2301264. DOI: 10.1002/adhm.202301264.
[43]	LiL, QianY, JiangC, et al. The use of hyaluronan to regulate protein adsorption and cell infiltration in nanofibrous scaffolds[J]. Biomaterials, 2012,33(12):3428-3445. DOI: 10.1016/j.biomaterials.2012.01.038.
[44]	LiuW, GaoR, YangC, et al. ECM-mimetic immunomodulatory hydrogel for methicillin-resistant Staphylococcus aureus-infected chronic skin wound healing[J]. Sci Adv, 2022,8(27):eabn7006. DOI: 10.1126/sciadv.abn7006.
[45]	QianY, ZhengY, JinJ, et al. Immunoregulation in diabetic wound repair with a photoenhanced glycyrrhizic acid hydrogel scaffold[J]. Adv Mater, 2022,34(29):e2200521. DOI: 10.1002/adma.202200521.

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Research advance on the effects of surface interface topographies and physicochemical properties of biomaterial on macrophages and their application in wound healing

doi: 10.3760/cma.j.cn501225-20231110-00190

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Research advance on the effects of surface interface topographies and physicochemical properties of biomaterial on macrophages and their application in wound healing

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