Email Alerts
RSS
Volume 40 Issue 7
Jul.  2024
Turn off MathJax
Article Contents
Article Navigation >  CHINESE JOURNAL OF BURNS AND WOUNDS  > 2024  >  40(7): 694-698
Liu HZ,Zhang Y,Gao C,et al.Research advances on in-situ cell electrospinning and its application in wound repair[J].Chin J Burns Wounds,2024,40(7):694-698.DOI: 10.3760/cma.j.cn501225-20231123-00204.
Citation: Liu HZ,Zhang Y,Gao C,et al.Research advances on in-situ cell electrospinning and its application in wound repair[J].Chin J Burns Wounds,2024,40(7):694-698.DOI: 10.3760/cma.j.cn501225-20231123-00204.
shu

Research advances on in-situ cell electrospinning and its application in wound repair

doi: 10.3760/cma.j.cn501225-20231123-00204
  • 1.

    School of Medicine, Shanghai University, Shanghai 200444, China

  • 2.

    School of Mechatronic Engineering and Automation, Shanghai University, Shanghai 200444, China

  • 3.

    Department of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Shanghai 200433, China

Funds:

General Program of National Natural Science Foundation of China 82372513, 61973206

More Information
    Abstract
  • Currently, there are limited strategies for convenient and rapid wound repair in clinical practice. In recent years, in-situ cell electrospinning (IS-CE) technology, developed from in-situ electrospinning (IS-E) technology, has emerged. IS-CE technology involves encapsulating living cells within micro-nanofibers to construct living fibrous tissue scaffolds in situ, making some progress in wound repair applications. However, this technology still faces limitations such as low cell survival rate and poor fiber stability. This article provides a comprehensive review on the current status of both IS-E and IS-CE technologies, as well as the application of IS-CE technology in wound repair. In addition, the advantages, limitations, and improvement methods of IS-CE technology applied in wound treatment are emphatically discussed, aiming to provide insights for its application in tissue engineering and wound repair.

     

    • FullText(HTML)
  • loading
    • References(42)
  • [1]
    ChenYE, FischbachMA, BelkaidY. Skin microbiota-host interactions[J]. Nature, 2018,553(7689):427-436. DOI: 10.1038/nature25177.
    [2]
    SunBK, SiprashviliZ, KhavariPA. Advances in skin grafting and treatment of cutaneous wounds[J]. Science, 2014,346(6212):941-945. DOI: 10.1126/science.1253836.
    [3]
    FarahaniM,ShafieeA.Wound healing: from passive to smart dressings[J].Adv Healthc Mater,2021,10(16):e2100477.DOI: 10.1002/adhm.202100477.
    [4]
    孟昭刚,张子璇.医用功能性敷料的研究进展[J].解放军预防医学杂志,2020,38(3):88-89,93.DOI: 10.13704/j.cnki.jyyx.2020.03.029.
    [5]
    赵守进, 刘哲鹏, 付子让, 等. 静电纺丝在组织工程学中的应用进展[J].生物医学工程学进展,2021,42(3):149-153,163. DOI: 10.3969/j.issn.1674-1242.2021.03.007.
    [6]
    杨冬, 贾彤彤, 雷蕾, 等. 静电纺丝技术制备医用敷料的研究进展[J].高分子通报,2022(9):1-7. DOI: 10.14028/j.cnki.1003-3726.2022.09.001.
    [7]
    YanX, YuM, RamakrishnaS, et al. Advances in portable electrospinning devices for in situ delivery of personalized wound care[J]. Nanoscale, 2019,11(41):19166-19178. DOI: 10.1039/c9nr02802a.
    [8]
    HongJ,YeoM,YangGH,et al.Cell-electrospinning and its application for tissue engineering[J].Int J Mol Sci,2019,20(24):6208.DOI: 10.3390/jms20246208.
    [9]
    XuS, LuT, YangL, et al. In situ cell electrospun using a portable handheld electrospinning apparatus for the repair of wound healing in rats[J]. Int Wound J, 2022,19(7):1693-1704. DOI: 10.1111/iwj.13769.
    [10]
    吴元强,许宁,陆振乾,等.静电纺丝设备的研究进展[J].合成纤维工业,2018,41(6):48-53.DOI: 10.3969/j.issn.1001-0041.2018.06.017.
    [11]
    XueJ, WuT, DaiY, et al. Electrospinning and electrospun nanofibers: methods, materials, and applications[J]. Chem Rev, 2019,119(8):5298-5415. DOI: 10.1021/acs.chemrev.8b00593.
    [12]
    谷润润,李利芳,吴业北,等.静电纺丝装置的关键部件研究进展[J].信息记录材料,2020,21(3):3-4. DOI: 10.16009/j.cnki.cn13-1295/tq.2020.03.002.
    [13]
    ZhengQ, XiY, WengY. Functional electrospun nanofibers: fabrication, properties, and applications in wound-healing process[J]. RSC Adv, 2024,14(5):3359-3378. DOI: 10.1039/d3ra07075a.
    [14]
    刘钟, 刘现峰, 王学艳, 等. 便携式静电纺丝装置在医学方面的应用[J].青岛大学学报(工程技术版),2021,36(4):40-54,61. DOI: 10.13306/j.1006-9798.2021.04.007.
    [15]
    ChenH,ZhangH,ShenY,et al.Instant in-situ tissue repair by biodegradable PLA/gelatin nanofibrous membrane using a 3D printed handheld electrospinning device[J].Front Bioeng Biotechnol,2021,9:684105. DOI: 10.3389/fbioe.2021.684105.
    [16]
    XuSC, QinCC, YuM, et al. A battery-operated portable handheld electrospinning apparatus[J]. Nanoscale, 2015,7(29):12351-12355. DOI: 10.1039/c5nr02922h.
    [17]
    LuoWL,ZhangJ,QiuX,et al.Electric-field-modified in situ precise deposition of electrospun medical glue fibers on the liver for rapid hemostasis[J].Nanoscale Res Lett,2018,13(1):278.DOI: 10.1186/s11671-018-2698-8.
    [18]
    ZhaoYT, ZhangJ, GaoY, et al. Self-powered portable melt electrospinning for in situ wound dressing[J]. J Nanobiotechnology, 2020,18(1):111. DOI: 10.1186/s12951-020-00671-w.
    [19]
    DongRH,LiY,ChenM, et al.In situ electrospinning of aggregation-induced emission nanofibrous dressing for wound healing[J].Small Methods,2022,6(5):e2101247.DOI: 10.1002/smtd.202101247.
    [20]
    于超群, 龙云泽, 刘现峰, 等. 载药静电纺丝纤维研究及应用进展[J].青岛大学学报(医学版),2023,59(1):147-150. DOI: 10.11712/jms.2096-5532.2023.59.048.
    [21]
    MaurmannN,FrançaFS,GirónJ,et al. Cell electrospinning: a review of materials and methodologies for biofabrication[J]. Adv Biol (Weinh),2023,7(10):e2300058. DOI: 10.1002/adbi.202300058.
    [22]
    YeoMG,KimGH.Fabrication of cell-laden electrospun hybrid scaffolds of alginate-based bioink and PCL microstructures for tissue regeneration[J].Chem Eng J,2015,275:27-35.DOI: 10.1016/j.cej.2015.04.038.
    [23]
    Townsend-NicholsonA, JayasingheSN. Cell electrospinning: a unique biotechnique for encapsulating living organisms for generating active biological microthreads/scaffolds[J]. Biomacromolecules, 2006,7(12):3364-3369. DOI: 10.1021/bm060649h.
    [24]
    ChenH, LiuY, HuQ. A novel bioactive membrane by cell electrospinning[J]. Exp Cell Res, 2015,338(2):261-266. DOI: 10.1016/j.yexcr.2015.08.007.
    [25]
    YeoM,KimGH. Anisotropically aligned cell-laden nanofibrous bundle fabricated via cell electrospinning to regenerate skeletal muscle tissue[J].Small,2018,14(48):e1803491.DOI: 10.1002/smll.201803491.
    [26]
    WenZ, ChenY, LiaoP, et al. In Situ Precision cell electrospinning as an efficient stem cell delivery approach for cutaneous wound healing[J]. Adv Healthc Mater, 2023,12(26):e2300970. DOI: 10.1002/adhm.202300970.
    [27]
    WuJ, HongY.Enhancing cell infiltration of electrospun fibrous scaffolds in tissue regeneration[J].Bioact Mater,2016,1(1):56-64.DOI: 10.1016/j.bioactmat.2016.07.001.
    [28]
    HuZ, QinZ, QuY, et al. Cell electrospinning and its application in wound healing: principles, techniques and prospects[J/OL]. Burns Trauma, 2023,11:tkad028[2023-11-23]. https://pubmed.ncbi.nlm.nih.gov/37719178/.DOI: 10.1093/burnst/tkad028.
    [29]
    NamJ,HuangY,AgarwalS, et al.Materials selection and residual solvent retention in biodegradable electrospun fibers[J].JAPS,2008,107(3):1547-1554.DOI: 10.1002/app.27063.
    [30]
    KhorshidiS, SoloukA, MirzadehH, et al. A review of key challenges of electrospun scaffolds for tissue-engineering applications[J]. J Tissue Eng Regen Med, 2016,10(9):715-738. DOI: 10.1002/term.1978.
    [31]
    OuyangL, YaoR, ZhaoY, et al. Effect of bioink properties on printability and cell viability for 3D bioplotting of embryonic stem cells[J]. Biofabrication, 2016,8(3):035020. DOI: 10.1088/1758-5090/8/3/035020.
    [32]
    KimYB,LeeH,KimGH.Strategy to achieve highly porous/biocompatible macroscale cell blocks,using a collagen/genipin-bioink and an optimal 3D printing process[J].ACS Appl Mater Interfaces,2016,8(47):32230-32240.DOI: 10.1021/acsami.6b11669.
    [33]
    ShariatpanahiSP,BonnD,EjtehadiMR,et al.Electrical bending instability in electrospinning visco-elastic solutions[J].J Polym Sci Part B: Polym Phys,2016,54(11):1036-1042.DOI: 10.1002/polb.24029.
    [34]
    OngCS, YesantharaoP, HuangCY, et al. 3D bioprinting using stem cells[J]. Pediatr Res, 2018,83(1/2):223-231. DOI: 10.1038/pr.2017.252.
    [35]
    ZhaoS, AgarwalP, RaoW, et al. Coaxial electrospray of liquid core-hydrogel shell microcapsules for encapsulation and miniaturized 3D culture of pluripotent stem cells[J]. Integr Biol (Camb), 2014,6(9):874-884. DOI: 10.1039/c4ib00100a.
    [36]
    卓丽云, 朱自明, 郑高峰. 环境温湿度对静电纺丝稳定喷射的影响[J].工程塑料应用,2020,48(3):61-65. DOI: 10.3969/j.issn.1001-3539.2020.03.011.
    [37]
    YangGZ,LiHP,YangJH,et al.Influence of working temperature on the formation of electrospun polymer nanofibers[J].Nanoscale Res Lett,2017, 12(1):55.DOI: 10.1186/s11671-016-1824-8.
    [38]
    史春梦. 加强难愈合创面间充质干细胞治疗的基础与转化研究[J].中华烧伤与创面修复杂志,2022,38(11):999-1003. DOI: 10.3760/cma.j.cn501225-20220913-00405.
    [39]
    ParkYR, JuHW, LeeJM, et al. Three-dimensional electrospun silk-fibroin nanofiber for skin tissue engineering[J]. Int J Biol Macromol, 2016,93(Pt B):1567-1574. DOI: 10.1016/j.ijbiomac.2016.07.047.
    [40]
    程飚, 付小兵. 微环境控制是实现创面完美修复的必由之路[J].中华烧伤杂志,2020,36(11):1003-1008. DOI: 10.3760/cma.j.cn501120-20201009-00429.
    [41]
    李晔, 杨育坤, 朱向情, 等. 间充质干细胞活体示踪:如何实现分布和存活的同时示踪[J].中国组织工程研究,2021,25(31):5025-5033.
    [42]
    文小虎, 马诗文, 姜世豪, 等. 应用于糖尿病溃疡的载药静电纺丝敷料研究进展[J].中国生物工程杂志,2023,43(2/3):54-63. DOI: 10.13523/j.cb.2208034.
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索
    Get Citation
    PDF
    XML

    Article Metrics

    Article views (90) PDF downloads(17) Cited by()
    Proportional views
    Related

    Copyright © Chinese Journal of Burns京ICP备07035254号-14

    E-mail：shaoshangzazhi@163.com

    Website：https://zhsszz.xml-journal.net/

    Supported by: Beijing Renhe Information Technology Co. Ltd    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return