Research advances on <i>in-situ</i> cell electrospinning and its application in wound repair

Liu Huazhen; Zhang Yi; Gao Chuang; Lu Chunxiang; Guo Zilong; Sun Wenbin; Xiao Shichu; Liu Yuanyuan

doi:10.3760/cma.j.cn501225-20231123-00204

Volume 40 Issue 7

Jul. 2024

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Article Navigation > CHINESE JOURNAL OF BURNS AND WOUNDS > 2024 > 40(7): 694-698

Liu HZ,Zhang Y,Gao C,et al.Research advances on in-situ cell electrospinning and its application in wound repair[J].Chin J Burns Wounds,2024,40(7):694-698.DOI: 10.3760/cma.j.cn501225-20231123-00204.

Citation:

Liu HZ,Zhang Y,Gao C,et al.Research advances on in-situ cell electrospinning and its application in wound repair[J].Chin J Burns Wounds,2024,40(7):694-698.DOI: 10.3760/cma.j.cn501225-20231123-00204.

Citation:

Liu HZ,Zhang Y,Gao C,et al.Research advances on in-situ cell electrospinning and its application in wound repair[J].Chin J Burns Wounds,2024,40(7):694-698.DOI: 10.3760/cma.j.cn501225-20231123-00204.

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Research advances on in-situ cell electrospinning and its application in wound repair

doi: 10.3760/cma.j.cn501225-20231123-00204

1.
School of Medicine, Shanghai University, Shanghai 200444, China
2.
School of Mechatronic Engineering and Automation, Shanghai University, Shanghai 200444, China
3.
Department of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Shanghai 200433, China

Funds:

General Program of National Natural Science Foundation of China 82372513, 61973206

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Corresponding author: Xiao Shichu, Email: huangzhuoxiao4@hotmail.com; Liu Yuanyuan, Email: yuanyuan_liu@shu.edu.cn
Received Date: 2023-11-23

Abstract

Abstract

Currently, there are limited strategies for convenient and rapid wound repair in clinical practice. In recent years, in-situ cell electrospinning (IS-CE) technology, developed from in-situ electrospinning (IS-E) technology, has emerged. IS-CE technology involves encapsulating living cells within micro-nanofibers to construct living fibrous tissue scaffolds in situ, making some progress in wound repair applications. However, this technology still faces limitations such as low cell survival rate and poor fiber stability. This article provides a comprehensive review on the current status of both IS-E and IS-CE technologies, as well as the application of IS-CE technology in wound repair. In addition, the advantages, limitations, and improvement methods of IS-CE technology applied in wound treatment are emphatically discussed, aiming to provide insights for its application in tissue engineering and wound repair.
- Nanofibers,
- Tissue scaffolds,
- Tissue engineering,
- In-situ cell electrospinning,
- Wound repair

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References(42)

References

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Research advances on in-situ cell electrospinning and its application in wound repair

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