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Article Navigation >  CHINESE JOURNAL OF BURNS AND WOUNDS  >  > Accepted Manuscript
Tao Ke,Cao Tao,Shao Luocheng.Echanism and thinking of Masquelet induced membrane technique in diabetic wound[J].Chin J Burns Wounds,2026,42(3):1-7.DOI: 10.3760/cma.j.cn501225-20251125-00487.
Citation: Tao Ke,Cao Tao,Shao Luocheng.Echanism and thinking of Masquelet induced membrane technique in diabetic wound[J].Chin J Burns Wounds,2026,42(3):1-7.DOI: 10.3760/cma.j.cn501225-20251125-00487.
shu

Echanism and thinking of Masquelet induced membrane technique in diabetic wound

doi: 10.3760/cma.j.cn501225-20251125-00487
  • 1.

    Department of Wound Repair, Center for Wound Repair and Regenerative Medicine, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325015, China

  • 2.

    Department of Cell Biology, National Center for Translational Science of Molecular Medicine, Air Force Medical University, Xi 'an 710032, China

Funds:

General Program of National Natural Science Foundation of China 82272269

More Information
  • Corresponding author: Tao Ke, Email: tao-ke2001@163.com
  • Received Date: 2025-11-25
    Available Online: 2026-03-10
    Abstract
  • Diabetic wounds are hindered in the healing process due to chronic inflammation caused by the high sugar microenvironment, vascularization disorder, and imbalance in the secretion of growth factors. Masquelet induced membrane technique creates a bioactive membrane composed of various cellular components and rich in growth factors and microvessels by implanting bone cement into the wound. The membrane mainly promotes wound healing by remodeling the inflammatory microenvironment, promoting functional angiogenesis, and producing endogenous growth factors. This article briefly explains the mechanism by which the induced membrane technology improves wound healing and summarizes its clinical application in diabetic wounds. It is expected to provide new ideas and effective means for the clinical treatment of difficult-to-heal diabetic wounds. Future research needs to focus on the key molecular pathways of induced membrane therapy and the development of new membrane induction materials, so as to provide new strategies for the treatment of diabetic wounds.

     

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