Turn off MathJax
Article Contents
Chen Tao,Deng Chengliang,Gao Shaoying,et al.Clinical application effects of vertical mattress suture combined with teardrop-shaped end-to-side arterial anastomosis technique in free flap transplantation for repairing limb wounds[J].Chin J Burns Wounds,2026,42(5):1-8.DOI: 10.3760/cma.j.cn501225-20260131-00061.
Citation: Chen Tao,Deng Chengliang,Gao Shaoying,et al.Clinical application effects of vertical mattress suture combined with teardrop-shaped end-to-side arterial anastomosis technique in free flap transplantation for repairing limb wounds[J].Chin J Burns Wounds,2026,42(5):1-8.DOI: 10.3760/cma.j.cn501225-20260131-00061.

Clinical application effects of vertical mattress suture combined with teardrop-shaped end-to-side arterial anastomosis technique in free flap transplantation for repairing limb wounds

doi: 10.3760/cma.j.cn501225-20260131-00061
Funds:

Traditional Chinese Medicine and Ethnic Medicine Scientific and Technological Research Project of Guizhou Provincial Administration of Traditional Chinese Medicine QZYY-2025-014

Science and Technology Fund Project of Guizhou Provincial Health Commission gzwjkj2024-155

Guizhou Provincial Clinical Medical Research Center for Wound Repair LCZX[2025]005

More Information
  • Corresponding author: Gao Shaoying, Email: 729414738@sjtu.edu.cn
  • Received Date: 2026-01-31
    Available Online: 2026-04-30
  •   Objective  To explore the clinical feasibility, safety, and effects of vertical mattress suture combined with teardrop-shaped end-to-side arterial anastomosis technique applied in free flap transplantation for repairing limb wounds.  Methods  This study was a case series study. From March 2023 to December 2024, 41 patients with skin and soft tissue defect wounds in limbs who met the inclusion criteria were admitted to the Department of Burn and Plastic Surgery of the Affiliated Hospital of Zunyi Medical University. Among them, there were 29 males and 12 females, aged from 39 to 74 years. After debridement, the wound areas ranged from 5.8 cm×3.5 cm to 17.5 cm×6.6 cm. The wounds were repaired with free anterolateral femoral perforator flaps, thoracodorsal artery perforator flaps, latissimus dorsi myocutaneous flaps, and medial sural artery perforator flaps, with flap areas of 8.0 cm×4.0 cm to 19.5 cm×7.0 cm. Due to atherosclerosis or even intimal delamination of recipient arteries, or significant mismatch in arterial diameters between the donor and recipient sites, the vertical mattress suture combined with teardrop-shaped end-to-side arterial anastomosis technique was used for arterial anastomosis of in the donor and recipient sites. The wounds in the donor site were directly closed after reducing tension. During the operation, the situation of atherosclerosis, intimal delamination, or significant mismatch in arterial diameters between the donor and recipient sites was observed. After surgery, the complete survival of the flaps was observed, and the complete flap survival rate was calculated. The occurrence of postoperative complications was recorded. During the follow-up after surgery, the color, texture, and hypertrophy of the surviving flaps, as well as scar hyperplasia in the donor site were observed. Before surgery and at the final follow-up, the functional recoveries of the affected limbs were assessed in patients with wounds in upper and lower limbs using the upper limb function index (UEFI) and foot function index (FFI), respectively. At the final follow-up, the satisfaction of patients with the appearance of the donor and recipient sites and the function of the affected limbs were recorded.  Results  During the operation, it was observed that 23 patients had atherosclerosis in the recipient artery anastomosis area, even with intimal delamination; in 18 patients, there was a significant difference in the diameter of the flap artery and the recipient artery, with the ratio ranging from 1.0:1.5 to 1.0:3.3, with an average of 1.0:2.4. After surgery, 40 patients had complete flap survival, with a complete flap survival rate of 97.6% (40/41). After surgery, five patients with infectious wounds had delayed suture healing, which healed after dressing changes. No arterial crisis occurred in all patients during hospitalization after surgery. During follow-up of 6 to 18 months after surgery, the surviving flaps had similar color and texture to the recipient skin, with a full appearance but not bloated. Only linear scars occurred in the donor site, with no obvious hypertrophic scar. Before surgery, the UEFI of upper limbs ranged from 29 to 54, with an average of 41; at the final follow-up, the UEFI of upper limbs ranged from 59 to 72, with an average of 73. Before surgery, the FFI of lower limbs ranged from 43 to 87, with an avarage of 73; at the final follow-up, the FFI of lower limbs ranged from 15 to 42, with an average of 29. At the final follow-up, 24 out of 28 patients with wounds in lower limbs were able to walk without the assistance of auxiliary tools; patients were satisfied with the appearance of the donor and recipient sites, as well as the functional recovery of the affected limbs.  Conclusions  The vertical mattress suture combined with teardrop-shaped end-to-side arterial anastomosis technique effectively achieves the eversion and apposition of the arterial intima, reduces the risk of dissection and stenosis at the arterial anastomosis site, and significantly improves the patency rate of the anastomosis site. This technique applied in free flap transplantation for repairing limb wounds can prevent arterial crisis, with high flap survival rate and satisfaction of patients after surgery, thus having application value in clinical practice.

     

  • loading
  • [1]
    DongKX,ZhouY,ChengYY,et al.Clinical application of digital technology in the use of anterolateral thigh lobulated perforator flaps to repair complex soft tissue defects of the limbs[J/OL].Burns Trauma,2024,12:tkae011[2026-01-31].https://pubmed.ncbi.nlm.nih.gov/38737342/. DOI: 10.1093/burnst/tkae011.
    [2]
    HuangK,MiB,XiongY,et al.Angiogenesis during diabetic wound repair: from mechanism to therapy opportunity[J/OL].Burns Trauma,2025,13:tkae052[2026-01-31].https://pubmed.ncbi.nlm.nih.gov/39927093/. DOI: 10.1093/burnst/tkae052.
    [3]
    葛成伟,蒋国栋,程俊楠,等.以旋股外侧动脉斜支为蒂并携带阔筋膜的股前外侧穿支皮瓣修复手足毁损性创面并重建功能的效果[J].中华烧伤与创面修复杂志,2024,40(9):842-848.DOI: 10.3760/cma.j.cn501225-20240508-00163.
    [4]
    简扬,魏在荣,陈伟,等.游离皮瓣在糖尿病足溃疡修复中的应用研究进展[J].中华烧伤与创面修复杂志,2023,39(4):376-380.DOI: 10.3760/cma.j.cn501225-20221216-00539.
    [5]
    BroerPN,MoellhoffN,MayerJM,et al.Comparison of outcomes of end-to-end versus end-to-side anastomoses in lower extremity free flap reconstructions[J].J Reconstr Microsurg,2020,36(6):432-437.DOI: 10.1055/s-0040-1702156.
    [6]
    CaiA,HorchRE,ArkudasA.The impossible anastomosis: intima-to-adventitia suture technique for microanastomosis of severely calcified arteries[J].Plast Reconstr Surg Glob Open,2021,9(10):e3866.DOI: 10.1097/GOX.0000000000003866.
    [7]
    OkazakiM,AsatoH,SarukawaS,et al.Availability of end-to-side arterial anastomosis to the external carotid artery using short-thread double-needle microsuture in free-flap transfer for head and neck reconstruction[J].Ann Plast Surg,2006,56(2):171-175.DOI: 10.1097/01.sap.0000197620.03306.2f.
    [8]
    LinPC, ConstantinoNLC, LinTS. Modified funneling arterial microanastomosis in large vessels size mismatch[J]. J Plast Reconstr Aesthet Surg, 2024, 99:392-394. DOI: 10.1016/j.bjps.2024.10.030.
    [9]
    徐永清,唐举玉,刘元波,等.股前外侧皮瓣穿支解剖学特征与定位方法的专家共识(2024版)[J].中国临床解剖学杂志,2024,42(5):489-499.DOI: 10.13418/j.issn.1001-165x.2024.5.01.
    [10]
    HsiehF,LeowO,CheongCF,et al.Musculoseptocutaneous perforator of anterolateral thigh flap: a clinical study[J].Plast Reconstr Surg,2021,147(1):103e-110e.DOI: 10.1097/PRS.0000000000007471.
    [11]
    BurusapatC,NanasilpT,KunaphensaengP,et al.Effect of atherosclerosis on the lateral circumflex femoral artery and its descending branch: comparative study to nonatherosclerotic risk[J].Plast Reconstr Surg Glob Open,2016,4(9):e856.DOI: 10.1097/GOX.0000000000000849.
    [12]
    OuCL,LiJ,ZhouX,et al.Repair of multiple hand defects with superficial circumflex iliac artery perforator flap[J].Injury,2023,54(3):940-946.DOI: 10.1016/j.injury.2023.01.016.
    [13]
    TungYC,ChenYK,LinYS.Reconstruction of posttraumatic distal limb defects with free superficial circumflex iliac artery perforator flap[J].Ann Plast Surg,2025,94(3S Suppl 1):S13-S17.DOI: 10.1097/SAP.0000000000004198.
    [14]
    TuluyY,Özkaya ÜnsalM,BaliZU,et al.Reconstruction of plantar foot defects with free super-thin anterolateral thigh flap[J].ANZ J Surg,2024,94(3):461-466.DOI: 10.1111/ans.18853.
    [15]
    FelderJM,NageebE,RochaI,et al.The role of flaps in preventing lower extremity amputations[J].Semin Vasc Surg,2025,38(1):64-73.DOI: 10.1053/j.semvascsurg.2025.01.013.
    [16]
    肖顺娥,李海,张天华,等.抗生素骨水泥植入联合游离嵌合组织瓣移植序贯治疗严重痛风性创面的临床效果[J].中华烧伤与创面修复杂志,2025,41(1):53-60.DOI: 10.3760/cma.j.cn501225-20240919-00340.
    [17]
    张卫东,张伟,龚翔,等.超薄腹股沟皮瓣游离移植修复手足创面的效果[J].中华烧伤与创面修复杂志,2026,42(1):57-65.DOI: 10.3760/cma.j.cn501225-20241015-00390.
    [18]
    ShiY,SuY,YangX,et al.Computed tomography angiography-guided precise flap surgery: a new strategy for flap selection, mapping and harvesting[J/OL].Burns Trauma,2024,12:tkae032[2026-01-31].https://pubmed.ncbi.nlm.nih.gov/38957663/. DOI: 10.1093/burnst/tkae032.
    [19]
    GaoY,YangE,LuoS,et al.Pre-expanded muscle-sparing latissimus dorsi flap in defect reconstruction and its application strategy[J/OL].Burns Trauma,2024,12:tkae014[2026-01-31].https://pubmed.ncbi.nlm.nih.gov/38898890/. DOI: 10.1093/burnst/tkae014.
    [20]
    张卫东,张伟,余刚,等.腓肠内侧动脉穿支皮瓣游离移植修复手足电烧伤创面的效果[J].中华烧伤与创面修复杂志,2025,41(4):386-393.DOI: 10.3760/cma.j.cn501225-20240611-00226.
    [21]
    BejerA,PłockiJ,KulczykM,et al.Adaptation of the upper limb functional index (ULFI) to a Polish version and validation in patients with upper limb musculoskeletal disorders[J].BMC Musculoskelet Disord,2025,26(1):506.DOI: 10.1186/s12891-025-08758-x.
    [22]
    XueB,PanY,WangB,et al.Simultaneous reconstruction of tibial osteomyelitis-complicated soft tissue defects using free flap transplantation in conjunction with the masquelet technique: a retrospective study[J].BMC Musculoskelet Disord,2024,25(1):891.DOI: 10.1186/s12891-024-08026-4.
    [23]
    OpyrchalJ,KrakowczykD,BulaD,et al.Overcoming the weight of reconstruction-anterolateral thigh flap reconstructions of the weight-bearing surface within the foot. Outcome assessment using foot function index[J].Eur J Orthop Surg Traumatol,2025,35(1):147.DOI: 10.1007/s00590-025-04270-z.
    [24]
    DeldarR,SayyedAA,CachG,et al.The use of flap techniques to preserve limb length in patients with transmetatarsal amputations[J].Plast Reconstr Surg,2024,153(4):944-954.DOI: 10.1097/PRS.0000000000010815.
    [25]
    XuZB,DaiGG,SunZY,et al.Application of antibiotic bone cement combined with lobulated perforator flap based on descending branch of the lateral circumflex femoral artery in treatment of infected traumatic tissue defects of foot[J].BMC Musculoskelet Disord,2024,25(1):673.DOI: 10.1186/s12891-024-07810-6.
    [26]
    HuangY,CaoY,YangL,et al.Comparative study of the morphological characteristics of perforators of the transverse and descending branches of the lateral circumflex femoral artery in anterolateral thigh flap surgery[J].Ann Plast Surg,2024,92(3):306-312.DOI: 10.1097/SAP.0000000000003766.
    [27]
    AcartürkTO,BengürFB.Individually tailored approach to reconstruction of complex defects using versatility of the lateral circumflex femoral artery system-based pedicled flaps[J].J Plast Reconstr Aesthet Surg,2022,75(1):199-209.DOI: 10.1016/j.bjps.2021.08.035.
    [28]
    QingL,LuoG,LiX,et al.Individualized design of thoracodorsal artery perforator chimeric flap for customized reconstruction of complex three-dimensional defects in the extremities[J].J Orthop Surg Res,2023,18(1):367.DOI: 10.1186/s13018-023-03852-z.
    [29]
    ParkJW,ParkBY.Angle-adjusted transverse thoracodorsal artery perforator flap in lower extremity reconstruction: a case series of 63 patients[J].Microsurgery,2025,45(1):e70001.DOI: 10.1002/micr.70001.
    [30]
    XieZ,CaoZM,YangY,et al.Clinical effect of free chimeric anterolateral thigh flap and chimeric thoracodorsal artery perforator flap in chronic osteomyelitis[J].J Plast Reconstr Aesthet Surg,2024,98:272-280.DOI: 10.1016/j.bjps.2024.09.007.
    [31]
    LinCT,WuSZ,ChenLW.Strategy of harvesting extended thoracodorsal artery perforator flaps for resurfacing the large soft-tissue defects of extremities[J].J Plast Reconstr Aesthet Surg,2022,75(3):1064-1072.DOI: 10.1016/j.bjps.2021.11.035.
    [32]
    GattoA,ParisiP,BrambillaL,et al.Thoracodorsal artery perforator flap, muscle-sparing latissimus dorsi, and descending branch latissimus dorsi: a multicenter retrospective study on early complications and meta-analysis of the literature[J].J Plast Reconstr Aesthet Surg,2022,75(11):3979-3996.DOI: 10.1016/j.bjps.2022.06.083.
    [33]
    HaY,LeeBH,ParkJA,et al.Reconstruction of soft tissue defect around knee with thoracodorsal artery perforator flap and muscle-sparing latissimus dorsi flap[J].Microsurgery,2023,43(7):665-675.DOI: 10.1002/micr.31024.
    [34]
    HsiehYH,WeiHI,HsuCC,et al.Evolution and diversity of medial sural artery perforator flap for hand reconstruction[J].Hand Clin,2024,40(2):209-220.DOI: 10.1016/j.hcl.2023.08.008.
    [35]
    LinCH,HsiehYH,LinCH.The medial sural artery perforator flap in lower extremity reconstruction[J].Clin Plast Surg,2021,48(2):249-257.DOI: 10.1016/j.cps.2021.01.003.
    [36]
    SuiX,KhanUZ,QingL,et al.The free chimeric medial sural artery perforator flap for individualised and three-dimensional reconstruction of complex soft-tissue defects in extremities[J].Int Wound J,2023,20(7):2679-2687.DOI: 10.1111/iwj.14142.
    [37]
    FengAL,SpectorME,ChinnSB,et al.Cross-legged modification for medial sural artery perforator flap harvest[J].Head Neck,2023,45(3):752-756.DOI: 10.1002/hed.27263.
    [38]
    Al-HimdaniS,DinA,WrightTC,et al.The medial sural artery perforator (MSAP) flap: a versatile flap for lower extremity reconstruction[J].Injury,2020,51(4):1077-1085.DOI: 10.1016/j.injury.2020.02.060.
    [39]
    林炳敏,董岩,蒋欣东,等.游离腓肠内侧动脉穿支皮瓣修复足背部软组织缺损12例[J].中华显微外科杂志,2025,48(4):444-447.DOI: 10.3760/cma.j.cn441206-20250210-00030.
    [40]
    LeeCH,ChenSH.Soft tissue reconstruction in the extremities: principles, techniques, and outcomes[J].Semin Plast Surg,2025,39(3):140-148.DOI: 10.1055/s-0045-1809975.
  • 陈涛 4月30日.mp4
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(4)

    Article Metrics

    Article views (98) PDF downloads(1) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return