2021 Vol. 37, No. 8

2021, 37(8): F01-F01. doi: 10.3760/cma.j.issn.1009-2587.2021.37.101
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2021, 37(8): 757-757. doi: 10.3760/cma.j.issn.1009-2587.2021.37.102
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2021, 37(8): 769-769. doi: 10.3760/cma.j.issn.1009-2587.2021.37.103
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Expert Forum
Clinical application and mechanism of botulinum toxin type A in scar treatment
Zhang Yixin, Zhang Shunuo
2021, 37(8): 705-710. doi: 10.3760/cma.j.cn501120-20210701-00232
Abstract:
Pathological scars cause both local physical discomforts and mental disorders for patients. With the development of research, botulinum toxin type A (BTX-A) has been gradually used in the clinical treatment of scars. This article summarizes three potential mechanisms of BTX-A, including early tensio...
Original Articles·Scar Treatment
Clinical effect of fractional carbon dioxide laser in the treatment of contracture scars
Xi Wenjing, Zhang Zheng, Li Jie, Su Weijie, Li Hua, Pu Zheming, Zhang Yan, Feng Shaoqing, Zhang Yixin
2021, 37(8): 711-717. doi: 10.3760/cma.j.cn501120-20210624-00225
Abstract:
Objective To explore the clinical effect of the fractional carbon dioxide laser in the treatment of contracture scars. Methods A retrospective before-after self-control study was conducted. From December 2016 to April 2021, 16 patients (7 males and 9 females, aged 3-49 years) with contracture scars ...
Clinical effects of follicle unit extraction transplantation combined with recombinant bovine basic fibroblast growth factor and minoxidil in the treatment of secondary cicatricial alopecia
Yang Qing, Xue Ping, Dou Wenjie, Fan Xing, Song Baoqiang
2021, 37(8): 718-724. doi: 10.3760/cma.j.cn501120-20210416-00132
Abstract:
Objective To explore the clinical effects of follicle unit extraction (FUE) transplantation combined with recombinant bovine basic fibroblast growth factor (rb-bFGF) gel and minoxidil tincture in treating secondary cicatricial alopecia (hereinafter referred to as cicatricial alopecia). Methods A ret...
Expression of microRNA-296 in rabbit hypertrophic scars and its role to human fibroblasts
Guo Bingyu, Lin Feng, Bai Zeming, Tao Kai, Wang Hongyi
2021, 37(8): 725-730. doi: 10.3760/cma.j.cn501120-20210420-00142
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Objective To investigate the expression of microRNA-296 (miR-296) in rabbit hypertrophic scars and its role in human fibroblasts (HFbs). Methods The experimental method was used. Twelve healthy adult New Zealand long-eared rabbits regardless gender were randomly divided into normal control group and...
Original Articles
A prospective study of the effect and mechanism of autologous platelet-rich plasma combined with Meek microskin grafts in repairing the wounds of limbs in severely burned patients
Zheng Jiansheng, Liu Shengli, Peng Xiaojing, Liu Xiaofei, Yu Le, Liang Shengqiang
2021, 37(8): 731-737. doi: 10.3760/cma.j.cn501120-20200427-00241
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Objective To observe the effect of autologous platelet-rich plasma (PRP) combined with Meek microskin grafts in repairing the wounds of limbs in severely burned patients, and to explore the mechanism. Methods The prospective controlled research method was used. From September 2016 to January 2020, 1...
Analysis of the clinical features and prognostic influencing factors of toxic epidermal necrolysis
Hu Zhengxiang, Bian Huining, Ma Dan, Luo Hongmin, Sun Chuanwei, Lai Wen
2021, 37(8): 738-746. doi: 10.3760/cma.j.cn501120-20200416-00230
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Objective To investigate the clinical features and prognostic influencing factors of toxic epidermal necrolysis (TEN). Methods A retrospective observational study was conducted. From January 2008 to March 2019, a total of 46 TEN patients who met the inclusion criteria were admitted to Guangdong Prov...
Application value of flexible endoscopy and rigid endoscopy in the clinical examination of chronic sinus tract wounds with different shapes
Tao Guilu, Liu Yingkai, Tang Jiajun, Ma Xian, Huang Lifang, Zhou Jingqi, Wu Fangyi, Yakupu Aobuliaximu, Wang Hanqi, Guan Haonan, Dong Jiaoyun, Lu Shuliang
2021, 37(8): 747-751. doi: 10.3760/cma.j.cn501120-20200318-00179
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Objective To explore the application value of flexible endoscopy and rigid endoscopy in the clinical examination of chronic sinus tract wounds with different shapes. Methods A retrospective observational study was conducted. From January 1 to December 23, 2019, a total of 46 patients with chronic si...
Clinical effects of expanded flap in repairing the wounds with exposed titanium mesh after cranioplasty with titanium mesh
Ji Peng, Hu Dahai, Han Fu, Yang Chen, Zhang Zhi, Tong Lin, Zhang Yue, Han Juntao, Tao Ke
2021, 37(8): 752-757. doi: 10.3760/cma.j.cn501120-20200613-00306
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Objective To explore the clinical effects of expanded flap made by skin and soft tissue expander (hereinafter referred to as expander) in repairing the wounds with exposed titanium mesh after cranioplasty with titanium mesh. Methods A retrospective observational study was conducted. From April 2015 ...
Clinical effects of neurocutaneous vascular flap innervated by terminal branch of lateral antebrachial cutaneous nerve in repairing finger tip or finger pulp wounds of the thumb
Wang Hui, Yang Xiaoxi, Huo Yongxin, Hao Ruizheng, Chang Hong, Liu Wei, Wang Bin
2021, 37(8): 758-763. doi: 10.3760/cma.j.cn501120-20200607-00298
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Objective To investigate the clinical effects of neurocutaneous vascular flap innervated by terminal branch of lateral antebrachial cutaneous nerve in repairing finger tip or finger pulp wounds of the thumb. Methods A retrospective observational study was conducted. From February 2016 to April 2019,...
Application of metagenomic next-generation sequencing technology in pathogen detection in patients with burns and patients with acute or chronic wounds
Li Feng, Yin Huinan, Hu Quan, Zhang Qinxue, Chen Qi, Yang Longlong, Chen Xin, Sun Yingjie
2021, 37(8): 764-769. doi: 10.3760/cma.j.cn501120-20200623-00322
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Objective To explore the value of using metagenomic next-generation sequencing (mNGS) technology to detect pathogens in patients with burns and patients with acute or chronic wounds. Methods A retrospective observational study was conducted. From March 2019 to June 2020, 11 patients with burns and p...
Biological activity of biomimetic dermal papilla spheres prepared by culture of dermal papilla cells of mice based on hanging drops of gelatin methacrylate and its hair-inducing function in nude mice
Huang Gang, Chen Liang
2021, 37(8): 770-780. doi: 10.3760/cma.j.cn501120-20210330-00109
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Objective To investigate the biological activity of biomimetic dermal papilla spheres (DPSs) prepared by three-dimensionally cultured dermal papilla cells (DPCs) of mice based on the biomimetic microenvironment of gelatin methacrylate (GelMA) and hanging drop method and its hair-inducing function in...
Original Article·Nursing Column
A prospective before-after self-control study of the scenario simulation teaching of junior nurses in a burns department on the fluid resuscitation care of massive burn patients during shock stage
Xie Lin, Zhang Yin, Wang Jiayu, Yang Dingting, Teng Peimin, Wang Wenliang, Huang Yi
2021, 37(8): 781-787. doi: 10.3760/cma.j.cn501120-20201105-00456
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Objective To explore the effects of scenario simulation teaching of junior nurses in a burns department on the fluid resuscitation care of massive burn patients during shock stage. Methods From March 2018 to July 2019, 25 junior nurses fixed in the Department of Burn of Ruijin Hospital Affiliated to...
Wound Repair
Observation on the clinical effect of self-designed modified rhomboid skin flap in facial wound repair
Yi Lei, Dou Yi, Zhou Zengding, Li Xuechuan, Zheng Jiexin, Zhang Qin, Huan Jingning, Liu Yan
2021, 37(8): 788-792. doi: 10.3760/cma.j.cn501120-20200504-00250
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Objective To investigate the clinical effect of self-designed modified rhomboid flap in repairing rhomboid, round, and teardrop-shaped wounds on the face. Methods A retrospective observational study was conducted. From August 2018 to April 2020, 30 patients with facial lesions admitted into Ruijin H...
Technique and Method
Reliability study on establishing a rat tuberculosis wound model using Bacillus Calmette-Guérin
Zhou Keqiang, Su Yingjun, Jia Chiyu
2021, 37(8): 793-796. doi: 10.3760/cma.j.cn501120-20200531-00290
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Objective To evaluate the reliability of a rat tuberculous wound model established by injecting Bacillus Calmette-Guérin (BCG). Methods The experimental research was conducted. According to the random number table, fifteen 6-week-old male Sprague-Dawley rats were divided into normal control group an...
Lecture
Management of pediatric deep partial-thickness burn wounds
Liu Yan, Zhang Jie
2021, 37(8): 797-800. doi: 10.3760/cma.j.cn501120-20200512-00261
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Deep partial-thickness burns are the most common type of pediatric burns, in which hypertrophic scars usually develop, causing functional and cosmetic impairment. The choice of wound management method and surgical procedures for deep partial-thickness burn are often the issues that concern burn surg...
Reviews
Research advances on the mechanisms and prevention and treatment of patient self-inflicted lung injury
Ren Zhiguo, Zhu Feng
2021, 37(8): 801-804. doi: 10.3760/cma.j.cn501120-20200610-00302
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Researches have shown that lung injury due to excessive spontaneous breathing effort, that is, patient self-inflicted lung injury (P-SILI), may be the important manifestation and possible mechanism of ventilation-associated lung injury and ventilation-induced diaphragmatic dysfunction in acute respi...