中华烧伤与创面修复杂志

Exploring wound healing from the perspective of circadian rhythm regulation

Wang Dali, Qi Fang

2024, 40(5): 401-406. doi: 10.3760/cma.j.cn501225-20240122-00027

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Wound healing is a complex and finely regulated biological process involving a variety of cell types, such as immune cells, fibroblasts, keratinocytes, endothelial cells, and stem cells. In recent years, scientific research has unveiled the significant role of circadian rhythms in the regulation of ...

Coordinating tissue repair: molecular pathways controlling the function of harmful and repairing neutrophils

He Weifeng, Yan Lingfeng

2024, 40(5): 407-414. doi: 10.3760/cma.j.cn501225-20240306-00089

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Neutrophils are the most abundant circulating white blood cells and play an indispensable role as first responders of damaged tissue and infected sites in the early inflammatory response of healing. Neutrophils provide immediate host defense by engulfing and destroying pathogens, releasing cytotoxic...

Role and mechanism of Vγ4 T cell depletion in epidermal tissue repair after ultraviolet damage to mouse skin

Li Yashu, He Weifeng, Lyu Kaiyang

2024, 40(5): 415-424. doi: 10.3760/cma.j.cn501225-20240121-00026

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Objective To explore the role and mechanism of Vγ4 T cell depletion in epidermal tissue repair after ultraviolet damage to mouse skin. Methods The study was an experimental study. Fifty-four female C57BL/6J wild-type mice aged 6 to 8 weeks were divided into Vγ4 T cell depletion group and control gro...

Effects of recombinant human metallothionein-Ⅲ combined with wound dressing on wound healing of full-thickness skin defects in mice

Shen Xin, Sun Zuoyi, Zhang Rui, Xue Yuying

2024, 40(5): 425-432. doi: 10.3760/cma.j.cn501225-20231031-00164

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Objective To investigate the effects of recombinant human metallothionein-Ⅲ (rh-MT-Ⅲ) combined with wound dressing on wound healing of full-thickness skin defects in mice. Methods This study was an experimental study. Twenty-four half male and half female 6 weeks old Institute of Cancer Research mic...

Visualized analysis of research hotspots and evolutionary trends in the field of wound repair mechanism research

Zhao Jiuhong, Lyu Yehui, Lei Yihan

2024, 40(5): 433-442. doi: 10.3760/cma.j.cn501225-20240118-00022

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Objective To explore the research hotspots and evolutionary trends in the field of wound repair mechanism research. Methods This study was a bibliometric analysis study. English literature related to wound repair mechanism published in the core collection of Web of Science database from the establis...

Clinical efficacy of membrane induction technique combined with local myocutaneous flap in repairing sinus cavity pressure injury in the greater trochanteric region

Tong Lin, Zhang Wanfu, Han Fei, Guan Hao

2024, 40(5): 443-450. doi: 10.3760/cma.j.cn501225-20231029-00144

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Objective To investigate the clinical efficacy of membrane induction technique combined with local myocutaneous flap in repairing sinus cavity pressure injury in the greater trochanteric region. Methods The study was a retrospective case series study. From January 2020 to January 2023, 12 patients w...

Effects of advanced platelet-rich fibrin/chitosan thermosensitive hydrogel on full-thickness skin defect wound healing in diabetic rats

Xun Haoyi, Su Xiaowei, Hu Fangchao, Liu Xiangyu, Wu Yushou, Liu Tian, Sun Ran, Duan Hongjie, Chi Yunfei, Chai Jiake

2024, 40(5): 451-460. doi: 10.3760/cma.j.cn501225-20231020-00127

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Objective To prepare advanced platelet-rich fibrin (A-PRF)/chitosan thermosensitive hydrogel (hereinafter referred to as composite hydrogel) and explore the effects of composite hydrogel on full-thickness skin defect wound healing in diabetic rats. Methods This study was an experimental study. The c...

Effects of antibacterial absorbable suture closure in the repair of small range of bone defect wounds due to deep sternal wound infection after median thoracotomy

Li Hanhua, Xiong Bing, Liu Zu'an, Huang Zhifeng, Sun Chuanwei, Luo Hongmin, Ma Lianghua, Bian Huining, Zheng Shaoyi, Lai Wen

2024, 40(5): 461-467. doi: 10.3760/cma.j.cn501225-20231103-00178

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Objective To investigate the effects of antibacterial absorbable suture closure in the repair of small range of bone defect wounds due to deep sternal wound infection after median thoracotomy. Methods This study was a retrospective non-randomized clinical controlled study. A total of 32 patients (20...

Analysis of effects and influencing factors of continuous renal replacement therapy in severe burn patients complicated with acute kidney injury

Heng Xue, Li Changmin, Liu Wei, Li Ning, Yuan Zhiqiang, Peng Yizhi, Li Haisheng, Luo Gaoxing

2024, 40(5): 468-475. doi: 10.3760/cma.j.cn501225-20240207-00052

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Objective To preliminarily evaluate the effects and analyze the influencing factors of continuous renal replacement therapy (CRRT) in severe burn patients complicated with acute kidney injury (AKI). Methods This study was a retrospective case series study. From January 2010 to December 2020, 79 seve...

Clinical effects of free dorsal interosseous artery perforator flaps in repairing multi-finger skin and soft tissue defects

Zheng Yun, Cheng Liangkun, Cui Liuchao, Tan Yuzhong, Tian Lin

2024, 40(5): 476-481. doi: 10.3760/cma.j.cn501225-20231130-00221

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Objective To investigate the clinical effects of free dorsal interosseous artery perforator flaps in repairing multi-finger skin and soft tissue defects. Methods The study was a retrospective observational study. From April 2020 to June 2022, 7 patients with multi-finger skin and soft tissue defects...

Analysis on the misuse of chi-square test

Zhang Pingyuan, Wang Kaifa

2024, 40(5): 482-488. doi: 10.3760/cma.j.cn501225-20240103-00004

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Count data are very common in biomedical research, and such kind of data is often organized in the form of contingency table. For count data, the common research purpose is to test whether two factors are independent, therefore chi-square test is often used for statistical analysis, but it is easy t...

Research advances on the influence of wound external microenvironment factors on wound healing

Cai Chenghao, Han Chunmao, Wang Xingang

2024, 40(5): 489-494. doi: 10.3760/cma.j.cn501225-20230827-00067

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Wound microenvironment is directly related to the speed and quality of wound healing, and it is composed of various physical, chemical, and biological factors, and these factors are in a dynamic balance under normal conditions. In order to understand the effects of various physical, chemical, and bi...

Research advances on the role of adipokines in diabetic peripheral arterial diseases

Lu Ting, Liu Amin, Jin Qihui, Zhang Ling

2024, 40(5): 495-500. doi: 10.3760/cma.j.cn501225-20230724-00017

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Peripheral arterial disease is one of the common complications of diabetes. At present, the pathogenesis of diabetic peripheral arterial diseases is not completely clear, and there is a lack of effective treatment methods and drugs. Adipokines have profound impact on the occurrence and development o...

2024 Vol. 40, No. 5

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